A Candidate Gene Association Study for Economically Important Traits in Czech Dairy Goat Breeds

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12220%2F21%3A43902926" target="_blank" >RIV/60076658:12220/21:43902926 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027014:_____/21:N0000079 RIV/00027162:_____/21:N0000089

Výsledek na webu

<a href="https://doi.org/10.3390/ani11061796" target="_blank" >https://doi.org/10.3390/ani11061796</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ani11061796" target="_blank" >10.3390/ani11061796</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A Candidate Gene Association Study for Economically Important Traits in Czech Dairy Goat Breeds

Popis výsledku v původním jazyce

Simple Summary The milk production traits of goats are economically important. In the Czech Republic, goat milk is processed directly on farms and distributed as cheese. Although goat breeding is not a main focus of animal production in the Czech Republic, it is essential for the agricultural sector. A group of 14 SNPs (single-nucleotide polymorphisms) within four candidate genes (ACACA, BTN1A1, LPL, and SCD) were analysed in two Czech dairy goat breeds, White Shorthaired (WSH) goats and Brown Shorthaired (BSH) goats. The SNPs were significantly associated with milk-production traits (daily milk yield, protein, and fat percentage) and somatic cell count. This information may be useful for marker-assisted selection or related techniques to increase the accuracy of selection. Milk production is influenced by many factors, including genetic and environmental factors and their interactions. Animal health, especially udder health, is usually evaluated by the number of somatic cells. The present study described the effect of polymorphisms in the ACACA, BTN1A1, LPL, and SCD genes on the daily milk yield, fat, and protein percentages and somatic cell count. In this study, 590 White Shorthaired (WSH) and Brown Shorthaired (BSH) goats were included. SNP genotyping was performed by PCR-RFLP and multiplex PCR followed by SNaPshot minisequencing analysis. The linear mixed model with repeated measurement was used to identify the genetic associations between the studied genes/SNPs and chosen traits. All selected genes were polymorphic in the tested goat populations and showed significant associations with milk traits. Only BTN1A1 (SNP g.599 A &gt; G) showed a significant association with the somatic cell score. After Bonferroni correction, a significant effect of LPL g.300G &gt; A on daily milk yield and fat percentage, LPL g.185G &gt; T on protein percentage, and LPL G50C, SCD EX3_15G &gt; A, and SCD EX3_68A &gt; G on fat percentage was found. The importance of environmental factors, such as the herd-year effect, month of milking, and lactation order on all milk performance indicators was confirmed.

Název v anglickém jazyce

A Candidate Gene Association Study for Economically Important Traits in Czech Dairy Goat Breeds

Popis výsledku anglicky

Simple Summary The milk production traits of goats are economically important. In the Czech Republic, goat milk is processed directly on farms and distributed as cheese. Although goat breeding is not a main focus of animal production in the Czech Republic, it is essential for the agricultural sector. A group of 14 SNPs (single-nucleotide polymorphisms) within four candidate genes (ACACA, BTN1A1, LPL, and SCD) were analysed in two Czech dairy goat breeds, White Shorthaired (WSH) goats and Brown Shorthaired (BSH) goats. The SNPs were significantly associated with milk-production traits (daily milk yield, protein, and fat percentage) and somatic cell count. This information may be useful for marker-assisted selection or related techniques to increase the accuracy of selection. Milk production is influenced by many factors, including genetic and environmental factors and their interactions. Animal health, especially udder health, is usually evaluated by the number of somatic cells. The present study described the effect of polymorphisms in the ACACA, BTN1A1, LPL, and SCD genes on the daily milk yield, fat, and protein percentages and somatic cell count. In this study, 590 White Shorthaired (WSH) and Brown Shorthaired (BSH) goats were included. SNP genotyping was performed by PCR-RFLP and multiplex PCR followed by SNaPshot minisequencing analysis. The linear mixed model with repeated measurement was used to identify the genetic associations between the studied genes/SNPs and chosen traits. All selected genes were polymorphic in the tested goat populations and showed significant associations with milk traits. Only BTN1A1 (SNP g.599 A &gt; G) showed a significant association with the somatic cell score. After Bonferroni correction, a significant effect of LPL g.300G &gt; A on daily milk yield and fat percentage, LPL g.185G &gt; T on protein percentage, and LPL G50C, SCD EX3_15G &gt; A, and SCD EX3_68A &gt; G on fat percentage was found. The importance of environmental factors, such as the herd-year effect, month of milking, and lactation order on all milk performance indicators was confirmed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40101 - Agriculture

Projekt

<a href="/cs/project/QK1910320" target="_blank" >QK1910320: Výzkum postupů šlechtění dojeného skotu s cílem zvýšit odolnost k nemocem využitím genomických plemenných hodnot, rozvoje systému sběru zdravotních dat a cílené genotypizace skotu</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Animals

ISSN

2076-2615

e-ISSN

—

Svazek periodika

11

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

15

Strana od-do

1796

Kód UT WoS článku

000665477900001

EID výsledku v databázi Scopus

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