Association between louse abundance and MHC II supertypes in Galapagos mockingbirds
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F20%3A43901143" target="_blank" >RIV/60076658:12310/20:43901143 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/60077344:_____/20:00540769
Výsledek na webu
<a href="https://link.springer.com/article/10.1007/s00436-020-06617-3" target="_blank" >https://link.springer.com/article/10.1007/s00436-020-06617-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00436-020-06617-3" target="_blank" >10.1007/s00436-020-06617-3</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Association between louse abundance and MHC II supertypes in Galapagos mockingbirds
Popis výsledku v původním jazyce
Major histocompatibility complex class II (MHC II) is an essential molecule triggering the adaptive immune response by the presentation of pathogens to helper T cells. The association between individual MHC II variants and various parasites has become a frequent finding in studies of vertebrate populations. However, although bird ectoparasites have a significant effect on their host's fitness, and the host's immune system can regulate ectoparasitic infections, no study has yet investigated the association between MHC II polymorphism and ectoparasite infection in the populations of free-living birds. Here, we test whether an association exists between the abundance of a chewing louse (Myrsidea nesomimi) and MHC II polymorphism of its hosts, the Galapagos mockingbirds (Mimus). We have found that the presence of two MHC II supertypes (functionally differentiated clusters) was significantly associated with louse abundance. This pattern supports the theory that a co-evolutionary interaction stands behind the maintenance of MHC polymorphism. Moreover, we have found a positive correlation between louse abundance and heterophil/lymphocyte ratio (an indicator of immunological stress) that serves as an additional piece of evidence that ectoparasite burden is affected by immunological state of Galapagos mockingbirds.
Název v anglickém jazyce
Association between louse abundance and MHC II supertypes in Galapagos mockingbirds
Popis výsledku anglicky
Major histocompatibility complex class II (MHC II) is an essential molecule triggering the adaptive immune response by the presentation of pathogens to helper T cells. The association between individual MHC II variants and various parasites has become a frequent finding in studies of vertebrate populations. However, although bird ectoparasites have a significant effect on their host's fitness, and the host's immune system can regulate ectoparasitic infections, no study has yet investigated the association between MHC II polymorphism and ectoparasite infection in the populations of free-living birds. Here, we test whether an association exists between the abundance of a chewing louse (Myrsidea nesomimi) and MHC II polymorphism of its hosts, the Galapagos mockingbirds (Mimus). We have found that the presence of two MHC II supertypes (functionally differentiated clusters) was significantly associated with louse abundance. This pattern supports the theory that a co-evolutionary interaction stands behind the maintenance of MHC polymorphism. Moreover, we have found a positive correlation between louse abundance and heterophil/lymphocyte ratio (an indicator of immunological stress) that serves as an additional piece of evidence that ectoparasite burden is affected by immunological state of Galapagos mockingbirds.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10613 - Zoology
Návaznosti výsledku
Projekt
<a href="/cs/project/GPP506%2F12%2FP529" target="_blank" >GPP506/12/P529: Koevoluce mezi Galapážskými drozdci (Mimus spp.) a jejich ektoparazity.</a><br>
Návaznosti
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2020
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Parasitology Research
ISSN
0932-0113
e-ISSN
—
Svazek periodika
119
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
9
Strana od-do
1597-1605
Kód UT WoS článku
000515812500003
EID výsledku v databázi Scopus
2-s2.0-85078930003