Novel targets and strategies to combat borreliosis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F20%3A43901182" target="_blank" >RIV/60076658:12310/20:43901182 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60077344:_____/20:00540545

Výsledek na webu

<a href="https://link.springer.com/article/10.1007%2Fs00253-020-10375-8" target="_blank" >https://link.springer.com/article/10.1007%2Fs00253-020-10375-8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00253-020-10375-8" target="_blank" >10.1007/s00253-020-10375-8</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Novel targets and strategies to combat borreliosis

Popis výsledku v původním jazyce

Lyme borreliosis is a bacterial infection that can be spread to humans by infected ticks and may severely affect many organs and tissues. Nearly four decades have elapsed since the discovery of the disease agent called Borrelia burgdorferi. Although there is a plethora of knowledge on the infectious agent and thousands of scientific publications, an effective way on how to combat and prevent Lyme borreliosis has not been found yet. There is no vaccine for humans available, and only one active vaccine program in clinical development is currently running. A spirited search for possible disease interventions is of high public interest as surveillance data indicates that the number of cases of Lyme borreliosis is steadily increasing in Europe and North America. This review provides a condensed digest of the history of vaccine development up to new promising vaccine candidates and strategies that are targeted against Lyme borreliosis, including elements of the tick vector, the reservoir hosts, and the Borrelia pathogen itself.

Název v anglickém jazyce

Novel targets and strategies to combat borreliosis

Popis výsledku anglicky

Lyme borreliosis is a bacterial infection that can be spread to humans by infected ticks and may severely affect many organs and tissues. Nearly four decades have elapsed since the discovery of the disease agent called Borrelia burgdorferi. Although there is a plethora of knowledge on the infectious agent and thousands of scientific publications, an effective way on how to combat and prevent Lyme borreliosis has not been found yet. There is no vaccine for humans available, and only one active vaccine program in clinical development is currently running. A spirited search for possible disease interventions is of high public interest as surveillance data indicates that the number of cases of Lyme borreliosis is steadily increasing in Europe and North America. This review provides a condensed digest of the history of vaccine development up to new promising vaccine candidates and strategies that are targeted against Lyme borreliosis, including elements of the tick vector, the reservoir hosts, and the Borrelia pathogen itself.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/GA17-21244S" target="_blank" >GA17-21244S: Charakterizace role genů Borrelia afzelii potřebných k diseminaci uvnitř infikovaného klíštěte v průběhu sání</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Applied Microbiology and Biotechnology

ISSN

0175-7598

e-ISSN

—

Svazek periodika

104

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

1915-1925

Kód UT WoS článku

000507785800002

EID výsledku v databázi Scopus

2-s2.0-85078242119