The need to unravel the twisted nature of the Borrelia burgdorferi sensu lato complex across Europe

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F20%3A43901352" target="_blank" >RIV/60076658:12310/20:43901352 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60077344:_____/20:00540547

Výsledek na webu

<a href="https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.000899" target="_blank" >https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.000899</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1099/mic.0.000899" target="_blank" >10.1099/mic.0.000899</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The need to unravel the twisted nature of the Borrelia burgdorferi sensu lato complex across Europe

Popis výsledku v původním jazyce

Lyme borreliosis is a vector-borne infection caused by bacteria under the Borrelia burgdorferi sensu lato complex, both in Europe and North America. Differential gene expression at different times throughout its infectious cycle allows the spirochete to survive very diverse environments within different mammalian hosts as well as the tick vector. To date, the vast majority of data about spirochetal proteins and their functions are from genetic studies carried out on North American strains of a single species, i.e. B. burgdorferi sensu stricto. The whole-genome sequences recently obtained for several European species/strains make it feasible to adapt and use genetic techniques to study inherent differences between them. This review highlights the crucial need to undertake independent studies of genospecies within Europe, given their varying genetic content and pathogenic potential, and differences in clinical manifestation.

Název v anglickém jazyce

The need to unravel the twisted nature of the Borrelia burgdorferi sensu lato complex across Europe

Popis výsledku anglicky

Lyme borreliosis is a vector-borne infection caused by bacteria under the Borrelia burgdorferi sensu lato complex, both in Europe and North America. Differential gene expression at different times throughout its infectious cycle allows the spirochete to survive very diverse environments within different mammalian hosts as well as the tick vector. To date, the vast majority of data about spirochetal proteins and their functions are from genetic studies carried out on North American strains of a single species, i.e. B. burgdorferi sensu stricto. The whole-genome sequences recently obtained for several European species/strains make it feasible to adapt and use genetic techniques to study inherent differences between them. This review highlights the crucial need to undertake independent studies of genospecies within Europe, given their varying genetic content and pathogenic potential, and differences in clinical manifestation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/GA17-21244S" target="_blank" >GA17-21244S: Charakterizace role genů Borrelia afzelii potřebných k diseminaci uvnitř infikovaného klíštěte v průběhu sání</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Microbiology-SGM

ISSN

1350-0872

e-ISSN

—

Svazek periodika

166

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

428-435

Kód UT WoS článku

000537845200003

EID výsledku v databázi Scopus

2-s2.0-85085904539