Proteome dataset of mouse macrophage cell line infected with tick-borne encephalitis virus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F20%3A43902036" target="_blank" >RIV/60076658:12310/20:43902036 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60077344:_____/20:00540941

Výsledek na webu

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939094/" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939094/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.dib.2019.105029" target="_blank" >10.1016/j.dib.2019.105029</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Proteome dataset of mouse macrophage cell line infected with tick-borne encephalitis virus

Popis výsledku v původním jazyce

We report the proteomic datasets on the mouse macrophage cell line PMJ2R infected with tick-borne encephalitis virus (TBEV) for two and six days. Data were acquired using shotgun ultra-high resolution mass spectrometry. Peptide identifications were done using the Mascot version 2.4 (Matrix Science), and quantification was performed by a label-free approach. Protein profiles of early (two days) and late (six days) stages of infection were compared between each other and the respective control samples. Protein profiles of infected and control samples differed in the number of identified proteins and their relative abundances. Proteins detected in the TBEV-infected cells were involved in various processes related to the infection, including defense response against the virus, regulation of viral process, negative regulation of viral genome replication, RNA binding, or innate immune response. Also, proteins specific for the early and late stages of infection were identified. (C) 2019 The Author(s). Published by Elsevier Inc.

Název v anglickém jazyce

Proteome dataset of mouse macrophage cell line infected with tick-borne encephalitis virus

Popis výsledku anglicky

We report the proteomic datasets on the mouse macrophage cell line PMJ2R infected with tick-borne encephalitis virus (TBEV) for two and six days. Data were acquired using shotgun ultra-high resolution mass spectrometry. Peptide identifications were done using the Mascot version 2.4 (Matrix Science), and quantification was performed by a label-free approach. Protein profiles of early (two days) and late (six days) stages of infection were compared between each other and the respective control samples. Protein profiles of infected and control samples differed in the number of identified proteins and their relative abundances. Proteins detected in the TBEV-infected cells were involved in various processes related to the infection, including defense response against the virus, regulation of viral process, negative regulation of viral genome replication, RNA binding, or innate immune response. Also, proteins specific for the early and late stages of infection were identified. (C) 2019 The Author(s). Published by Elsevier Inc.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

10608 - Biochemistry and molecular biology

Projekt

<a href="/cs/project/LTARF18021" target="_blank" >LTARF18021: Vývoj technologie pro časnou detekci klíšťové encefalitidy založené na změnách v genové expresi a produkci proteinů u antigen-prezentujících buněk</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Data in Brief

ISSN

2352-3409

e-ISSN

—

Svazek periodika

28

Číslo periodika v rámci svazku

FEB 2020

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

—

Kód UT WoS článku

000520402100219

EID výsledku v databázi Scopus

2-s2.0-85076895664