Gas aggregated Ag nanoparticles as the inorganic matrix for laser desorption/ionization mass spectrometry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F21%3A43902984" target="_blank" >RIV/60076658:12310/21:43902984 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60077344:_____/21:00541682 RIV/68378271:_____/21:00541682 RIV/00216208:11320/21:10436024 RIV/00216224:14310/21:00120868

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0169433220332268?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0169433220332268?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.apsusc.2020.148469" target="_blank" >10.1016/j.apsusc.2020.148469</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Gas aggregated Ag nanoparticles as the inorganic matrix for laser desorption/ionization mass spectrometry

Popis výsledku v původním jazyce

We report here on a nanoparticle-assisted laser desorption/ionization time-of-flight mass spectrometry (NP-LDI-TOF MS) for the detection of small molecules. This technique is based on the overcoating of a dried analyte by an array of silver nanoparticles produced by gas aggregation source. This allows for the spatially homogeneous distribution of nanoparticles over the analyte that may fully substitute a conventional organic matrix routinely used for the matrix-assisted laser desorption/ionization mass spectrometry and thus limit the possible interference of matrix with the low-mass molecules. Furthermore, it is shown that the intensity of the detected signal strongly correlates with the number of deposited Ag nanoparticles. At its optimum, that was found to correspond to the nanoparticle surface density of 3x10(3) NPs.mu m(-2), the detection limit was 3x10(-8) g.L-1 for riboflavin. Such a high detection limit, together with good reproducibility, excellent signal stability, and imaging capability, makes this technique a valuable alternative to other laser desorption/ionization-based detection methods.

Název v anglickém jazyce

Gas aggregated Ag nanoparticles as the inorganic matrix for laser desorption/ionization mass spectrometry

Popis výsledku anglicky

We report here on a nanoparticle-assisted laser desorption/ionization time-of-flight mass spectrometry (NP-LDI-TOF MS) for the detection of small molecules. This technique is based on the overcoating of a dried analyte by an array of silver nanoparticles produced by gas aggregation source. This allows for the spatially homogeneous distribution of nanoparticles over the analyte that may fully substitute a conventional organic matrix routinely used for the matrix-assisted laser desorption/ionization mass spectrometry and thus limit the possible interference of matrix with the low-mass molecules. Furthermore, it is shown that the intensity of the detected signal strongly correlates with the number of deposited Ag nanoparticles. At its optimum, that was found to correspond to the nanoparticle surface density of 3x10(3) NPs.mu m(-2), the detection limit was 3x10(-8) g.L-1 for riboflavin. Such a high detection limit, together with good reproducibility, excellent signal stability, and imaging capability, makes this technique a valuable alternative to other laser desorption/ionization-based detection methods.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20506 - Coating and films

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Applied surface science

ISSN

0169-4332

e-ISSN

—

Svazek periodika

541

Číslo periodika v rámci svazku

MAR 1 2021

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

—

Kód UT WoS článku

000608511200005

EID výsledku v databázi Scopus

2-s2.0-85096515703