Protective Roles of Calcium Channel Blocker Against Cadmium-Induced Physiological Stress in Freshwater Teleost Oncorhynchus mykiss

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F11%3A43881327" target="_blank" >RIV/60076658:12520/11:43881327 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s11270-011-0754-4" target="_blank" >http://dx.doi.org/10.1007/s11270-011-0754-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11270-011-0754-4" target="_blank" >10.1007/s11270-011-0754-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Protective Roles of Calcium Channel Blocker Against Cadmium-Induced Physiological Stress in Freshwater Teleost Oncorhynchus mykiss

Popis výsledku v původním jazyce

The roles of Verapamil on Cd-induced physiological stress in teleost Oncorhynchus mykiss were investigated in this study. Forty-eight juvenile rainbow trout were divided randomly into 4 groups, i.e., control group, VRP group (100 mýg/L VRP), Cd group (50mýg/L Cd2+) and VRP+Cd group (100 mýg/L VRP + 50 mýg/L Cd2+). After one week exposure, oxidative stress indices and antioxidant parameters were measured in gill and liver tissues and the behavioral changes were recorded. Compared with the control, Cd-induced stress was apparent as reflected by a serious oxidative stress in fish tissues, and abnormal behaviors observed. In the VRP+Cd group, the antioxidant defense system of fish returned to the control level and the fish behavioral abnormalism markedlydecreased. The results suggested that VRP could reduce the Cd-induced physiological stress in fish and provided further evidence that Cd2+ uptake through Ca2+ transport pathways in freshwater teleost.

Název v anglickém jazyce

Protective Roles of Calcium Channel Blocker Against Cadmium-Induced Physiological Stress in Freshwater Teleost Oncorhynchus mykiss

Popis výsledku anglicky

The roles of Verapamil on Cd-induced physiological stress in teleost Oncorhynchus mykiss were investigated in this study. Forty-eight juvenile rainbow trout were divided randomly into 4 groups, i.e., control group, VRP group (100 mýg/L VRP), Cd group (50mýg/L Cd2+) and VRP+Cd group (100 mýg/L VRP + 50 mýg/L Cd2+). After one week exposure, oxidative stress indices and antioxidant parameters were measured in gill and liver tissues and the behavioral changes were recorded. Compared with the control, Cd-induced stress was apparent as reflected by a serious oxidative stress in fish tissues, and abnormal behaviors observed. In the VRP+Cd group, the antioxidant defense system of fish returned to the control level and the fish behavioral abnormalism markedlydecreased. The results suggested that VRP could reduce the Cd-induced physiological stress in fish and provided further evidence that Cd2+ uptake through Ca2+ transport pathways in freshwater teleost.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GL - Rybářství

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Water Air and Soil Pollution

ISSN

0049-6979

e-ISSN

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Svazek periodika

220

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

293-299

Kód UT WoS článku

000293783700027

EID výsledku v databázi Scopus

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