Unsupervised Adaptive Filter for Baseline Thresholding and Elimination in Liquid Chromatography-Mass Spectrometry via Approximation of the Standard Deviation of Baseline Distribution in Retention Time Domain

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F13%3A43885199" target="_blank" >RIV/60076658:12520/13:43885199 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.akademiai.com/content/w371212023q78740/?genre=article&id=doi%3a10.1556%2fAChrom.25.2013.2.4" target="_blank" >http://www.akademiai.com/content/w371212023q78740/?genre=article&id=doi%3a10.1556%2fAChrom.25.2013.2.4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1556/AChrom.25.2013.2.4" target="_blank" >10.1556/AChrom.25.2013.2.4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Unsupervised Adaptive Filter for Baseline Thresholding and Elimination in Liquid Chromatography-Mass Spectrometry via Approximation of the Standard Deviation of Baseline Distribution in Retention Time Domain

Popis výsledku v původním jazyce

The omitting presence of a baseline (background, systemic noise, mobile phase) in liquid chromatography-mass spectrometry (LC-MS) measurements impedes objective analysis. Therefore, there is a demand to remove its contribution from the signal response. Elimination of baseline contribution is justified by increasing the data mining output, both qualitatively and quantitatively. Behavior of the baseline content is not perfectly constant on the time axis, and it is often necessary to experiment with gradient changes. However, the behavior could be parametrized using a technique derived from statistical moments. In this article, we propose adaptive thresholding as an unsupervised method for baseline removal from the measurement data. Results of a real analyte measurement are discussed to illustrate its efficiency.

Název v anglickém jazyce

Unsupervised Adaptive Filter for Baseline Thresholding and Elimination in Liquid Chromatography-Mass Spectrometry via Approximation of the Standard Deviation of Baseline Distribution in Retention Time Domain

Popis výsledku anglicky

The omitting presence of a baseline (background, systemic noise, mobile phase) in liquid chromatography-mass spectrometry (LC-MS) measurements impedes objective analysis. Therefore, there is a demand to remove its contribution from the signal response. Elimination of baseline contribution is justified by increasing the data mining output, both qualitatively and quantitatively. Behavior of the baseline content is not perfectly constant on the time axis, and it is often necessary to experiment with gradient changes. However, the behavior could be parametrized using a technique derived from statistical moments. In this article, we propose adaptive thresholding as an unsupervised method for baseline removal from the measurement data. Results of a real analyte measurement are discussed to illustrate its efficiency.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/ED2.1.00%2F01.0024" target="_blank" >ED2.1.00/01.0024: Jihočeské výzkumné centrum akvakultury a biodiverzity hydrocenóz</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ACTA CHROMATOGRAPHICA

ISSN

1233-2356

e-ISSN

—

Svazek periodika

25

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

HU - Maďarsko

Počet stran výsledku

17

Strana od-do

257-273

Kód UT WoS článku

000319748700004

EID výsledku v databázi Scopus

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