Molecular basis of spermatogenesis and sperm quality

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F17%3A43895317" target="_blank" >RIV/60076658:12520/17:43895317 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0016648016301083" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0016648016301083</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ygcen.2016.04.026" target="_blank" >10.1016/j.ygcen.2016.04.026</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Molecular basis of spermatogenesis and sperm quality

Popis výsledku v původním jazyce

Spermatozoan quality can be evaluated in different ways, here we focus on the analysis of DNA, RNA and epigenetic status of germ cells. These characterizations also can be the bases for explaining sperm quality at other levels, so we will see how some of these molecules could affect other sperm quality markers. Moreover, we consider the possibility of using some of these molecules as predictors of sperm quality in terms of the ability to produce healthy offspring. The relevant effect of different types of RNA molecules in germ line specification and spermatogenesis and the importance of germ cell DNA integrity and a proper epigenetic pattern will be also discussed. Although most studies at this level have been performed in mammals, some information is available for fish; these recent discoveries in fish models are included. We provide a general overview on how these molecules could have a deep influence in the final sperm quality.

Název v anglickém jazyce

Molecular basis of spermatogenesis and sperm quality

Popis výsledku anglicky

Spermatozoan quality can be evaluated in different ways, here we focus on the analysis of DNA, RNA and epigenetic status of germ cells. These characterizations also can be the bases for explaining sperm quality at other levels, so we will see how some of these molecules could affect other sperm quality markers. Moreover, we consider the possibility of using some of these molecules as predictors of sperm quality in terms of the ability to produce healthy offspring. The relevant effect of different types of RNA molecules in germ line specification and spermatogenesis and the importance of germ cell DNA integrity and a proper epigenetic pattern will be also discussed. Although most studies at this level have been performed in mammals, some information is available for fish; these recent discoveries in fish models are included. We provide a general overview on how these molecules could have a deep influence in the final sperm quality.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40103 - Fishery

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

General and Comparative Endocrinology

ISSN

0016-6480

e-ISSN

—

Svazek periodika

245

Číslo periodika v rámci svazku

1 May 2017

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

5-9

Kód UT WoS článku

000399063700002

EID výsledku v databázi Scopus

2-s2.0-84975735347