Chronic dietary toxicity of zinc oxide nanoparticles in common carp (Cyprinus carpio L.): Tissue accumulation and physiological responses

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F18%3A43895996" target="_blank" >RIV/60076658:12520/18:43895996 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12220/18:43895996 RIV/61989592:15310/18:73588050

Výsledek na webu

<a href="https://ac.els-cdn.com/S0147651317305195/1-s2.0-S0147651317305195-main.pdf?_tid=5a5c2bec-029a-11e8-bf59-00000aab0f6b&acdnat=1516972440_2f160b17f7a61beb7983048ec78b8cf8" target="_blank" >https://ac.els-cdn.com/S0147651317305195/1-s2.0-S0147651317305195-main.pdf?_tid=5a5c2bec-029a-11e8-bf59-00000aab0f6b&acdnat=1516972440_2f160b17f7a61beb7983048ec78b8cf8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ecoenv.2017.08.024" target="_blank" >10.1016/j.ecoenv.2017.08.024</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chronic dietary toxicity of zinc oxide nanoparticles in common carp (Cyprinus carpio L.): Tissue accumulation and physiological responses

Popis výsledku v původním jazyce

Concerns regarding the potential toxic effects of zinc oxide nanoparticles (ZnO NPs) on aquatic organisms are growing due to the fact that NPs may be released into aquatic ecosystems. This study aimed to investigate the effects of dietary exposure to ZnO NPs on juvenile common carp (Cyprinus carpio). Fish were fed a spiked diets at doses 50 and 500 mg of ZnO NPs per kg of feed for 6 weeks followed by a 2-week recovery period. Fish were sampled every 2 weeks for haematology trends, blood biochemistry measures, histology analyses, and determination of the accumulation of zinc in tissues. At the end of the exposure and post-exposure periods, fish were sampled for an assessment of lipid peroxidation levels. Dietborne ZnO NPs had no effects on haematology, blood biochemistry, and lipid peroxidation levels during the exposure period. After the recovery period, aspartate aminotransferase activity significantly (p &lt; 0.05) increased and alanine transferase activity significantly (p &lt; 0.05) decreased in the higher exposure group. The level of lipid peroxidation significantly (p &lt; 0.05) decreased in liver of treated fish after 2 weeks post-exposure period. A histological examination revealed mild histopathological changes in kidneys during exposure. Our results did not show a significant increase of zinc content at the end of experiment in any of tested organs. However, chronic dietary exposure to ZnO NPs might affect kidney and liver function.

Název v anglickém jazyce

Chronic dietary toxicity of zinc oxide nanoparticles in common carp (Cyprinus carpio L.): Tissue accumulation and physiological responses

Popis výsledku anglicky

Concerns regarding the potential toxic effects of zinc oxide nanoparticles (ZnO NPs) on aquatic organisms are growing due to the fact that NPs may be released into aquatic ecosystems. This study aimed to investigate the effects of dietary exposure to ZnO NPs on juvenile common carp (Cyprinus carpio). Fish were fed a spiked diets at doses 50 and 500 mg of ZnO NPs per kg of feed for 6 weeks followed by a 2-week recovery period. Fish were sampled every 2 weeks for haematology trends, blood biochemistry measures, histology analyses, and determination of the accumulation of zinc in tissues. At the end of the exposure and post-exposure periods, fish were sampled for an assessment of lipid peroxidation levels. Dietborne ZnO NPs had no effects on haematology, blood biochemistry, and lipid peroxidation levels during the exposure period. After the recovery period, aspartate aminotransferase activity significantly (p &lt; 0.05) increased and alanine transferase activity significantly (p &lt; 0.05) decreased in the higher exposure group. The level of lipid peroxidation significantly (p &lt; 0.05) decreased in liver of treated fish after 2 weeks post-exposure period. A histological examination revealed mild histopathological changes in kidneys during exposure. Our results did not show a significant increase of zinc content at the end of experiment in any of tested organs. However, chronic dietary exposure to ZnO NPs might affect kidney and liver function.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10511 - Environmental sciences (social aspects to be 5.7)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Ecotoxicology and Environmental Safety

ISSN

0147-6513

e-ISSN

—

Svazek periodika

147

Číslo periodika v rámci svazku

1/2018

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

110-116

Kód UT WoS článku

000416199700015

EID výsledku v databázi Scopus

2-s2.0-85027846751