Sledování endokrinních poruch u jelce tlouště (Leuciscus cephalus) v řece Vltavě

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12610%2F04%3A00005841" target="_blank" >RIV/60076658:12610/04:00005841 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Monitoring of endocrine disruption in chub (Leuciscus cephalus) from the Vltava River

Popis výsledku v původním jazyce

The purpose of this study was to investigate whether Leuciscus cephalus, a fish routinely used to assess the quality of surface water in Czech Republic, is suitable to indicate the presence of endocrine-disrupting chemicals. A variety of anthropogenic pollutants may disrupt reproductive endocrine function by altering hormone pathways that regulate reproductive processes in wildlife. Vitellogenin (VTG), a precursor of egg yolk is synthesized and secreted in the liver in response to natural estrogens in female fish. Therefore, the presence of VTG in male fish is a useful biomarker to identify estrogenic activity of natural or anthropogenic substances in aquatic environment. Samples of fish muscle were collected on monitored sites of the Vltava river (Czech Republic) for chemical analyses of PCB, HCB, DDT and its metabolites, HCH, OCS, and musk compounds concentrations. Vitellogenin (Vtg) concentration was measured in blood plasma of chub males (L. cephalus) using ELISA (Carp vitellogenin

Název v anglickém jazyce

Monitoring of endocrine disruption in chub (Leuciscus cephalus) from the Vltava River

Popis výsledku anglicky

The purpose of this study was to investigate whether Leuciscus cephalus, a fish routinely used to assess the quality of surface water in Czech Republic, is suitable to indicate the presence of endocrine-disrupting chemicals. A variety of anthropogenic pollutants may disrupt reproductive endocrine function by altering hormone pathways that regulate reproductive processes in wildlife. Vitellogenin (VTG), a precursor of egg yolk is synthesized and secreted in the liver in response to natural estrogens in female fish. Therefore, the presence of VTG in male fish is a useful biomarker to identify estrogenic activity of natural or anthropogenic substances in aquatic environment. Samples of fish muscle were collected on monitored sites of the Vltava river (Czech Republic) for chemical analyses of PCB, HCB, DDT and its metabolites, HCH, OCS, and musk compounds concentrations. Vitellogenin (Vtg) concentration was measured in blood plasma of chub males (L. cephalus) using ELISA (Carp vitellogenin

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DN - Vliv životního prostředí na zdraví

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Toxicology and Applied Pharmacology

ISSN

0041-008X

e-ISSN

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Svazek periodika

197

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

1

Strana od-do

191

Kód UT WoS článku

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EID výsledku v databázi Scopus

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