Vliv bisfenolu A a 17ß-estradiolu na diferenciaci pohlaví u dánia pruhovaného (Danio rerio)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12610%2F05%3A00006265" target="_blank" >RIV/60076658:12610/05:00006265 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Effect of exposure to bisphenol A and 17ß-estradiol on the sex differentiation in zebrafish (Danio rerio)

Popis výsledku v původním jazyce

The effects of bisphenol A and 17ß-estradiol on sex differentiation were investigated in the zebrafish, Danio rerio. The 20-day-old fry with undifferentiated gonads were fed with food containing bisphenol A at the dose of 500, 1000, 2000 mg.kg-1 and 17ß-estradiol at the dose of 20 mg.kg-1 diet for 45 days. Sex ratio and gonadal development after the chemical treatment were determined by histological examination of gonads. In the control group, the sex ratio of fry was 1:1 (female:male), i.e. 50% of females and 50% of males appeared. The sex of fry fed with 17ß-estradiol at the dose of 20 mg.kg-1 diet was all females. Feminization of the fry was induced by exogenic 17ß-estradiol. The sex of fry fed with bisphenol A at the dose of 500, 1000, 2000 mg.kg-1diet was 1.4:1 (p = 0.31), 3.8:1 (p = 0.01) and 11.5:1 (p < 0.01). Bisphenol A induced feminization of the fry at the two highest doses tested.

Název v anglickém jazyce

Effect of exposure to bisphenol A and 17ß-estradiol on the sex differentiation in zebrafish (Danio rerio)

Popis výsledku anglicky

The effects of bisphenol A and 17ß-estradiol on sex differentiation were investigated in the zebrafish, Danio rerio. The 20-day-old fry with undifferentiated gonads were fed with food containing bisphenol A at the dose of 500, 1000, 2000 mg.kg-1 and 17ß-estradiol at the dose of 20 mg.kg-1 diet for 45 days. Sex ratio and gonadal development after the chemical treatment were determined by histological examination of gonads. In the control group, the sex ratio of fry was 1:1 (female:male), i.e. 50% of females and 50% of males appeared. The sex of fry fed with 17ß-estradiol at the dose of 20 mg.kg-1 diet was all females. Feminization of the fry was induced by exogenic 17ß-estradiol. The sex of fry fed with bisphenol A at the dose of 500, 1000, 2000 mg.kg-1diet was 1.4:1 (p = 0.31), 3.8:1 (p = 0.01) and 11.5:1 (p < 0.01). Bisphenol A induced feminization of the fry at the two highest doses tested.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

ED - Fyziologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Veterinaria Brno

ISSN

0001-7213

e-ISSN

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Svazek periodika

74

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

287-291

Kód UT WoS článku

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EID výsledku v databázi Scopus

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