Fotosyntetický alveolát blízce příbuzný parazitům kmene Apicomplexa

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F08%3A00319108" target="_blank" >RIV/60077344:_____/08:00319108 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12310/08:00009766

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

A photosynthetic alveolate closely related to apicomplexan parasites

Popis výsledku v původním jazyce

Many parasitic Apicomplexa contain an unpigmented chloroplast remnant termed apicoplast, which is a target for malaria treatment. However, no close relative of apicomplexans with a functional photosynthetic plastid has yet been known. Here we describe anewly cultured organism that has ultrastructural features typical of alveolates, is phylogenetically related to apicomplexans, and contains a photosynthetic plastid. The plastid is surrounded by four membranes, is pigmented by chlorophyll a, and uses thecodon UGA to encode tryptophan in the psbA gene. This genetic feature has been found only in coccidian apicoplasts and various mitochondria. The UGA-Trp codon and phylogenies of plastid and nuclear ribosomal RNA genes indicate that the organism is the closest known photosynthetic relative to apicomplexan parasites and that its plastid shares an origin with the apicoplasts. The discovery provides a powerful model with which to study the evolution of parasitism in Apicomplexa.

Název v anglickém jazyce

A photosynthetic alveolate closely related to apicomplexan parasites

Popis výsledku anglicky

Many parasitic Apicomplexa contain an unpigmented chloroplast remnant termed apicoplast, which is a target for malaria treatment. However, no close relative of apicomplexans with a functional photosynthetic plastid has yet been known. Here we describe anewly cultured organism that has ultrastructural features typical of alveolates, is phylogenetically related to apicomplexans, and contains a photosynthetic plastid. The plastid is surrounded by four membranes, is pigmented by chlorophyll a, and uses thecodon UGA to encode tryptophan in the psbA gene. This genetic feature has been found only in coccidian apicoplasts and various mitochondria. The UGA-Trp codon and phylogenies of plastid and nuclear ribosomal RNA genes indicate that the organism is the closest known photosynthetic relative to apicomplexan parasites and that its plastid shares an origin with the apicoplasts. The discovery provides a powerful model with which to study the evolution of parasitism in Apicomplexa.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA206%2F06%2F1439" target="_blank" >GA206/06/1439: Molekulární charakterizace a fylogeneze symbiotických prvoků z korálů</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nature

ISSN

0028-0836

e-ISSN

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Svazek periodika

451

Číslo periodika v rámci svazku

21-02-2008

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

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Kód UT WoS článku

000253313100041

EID výsledku v databázi Scopus

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