Do clones degenerate over time? Explaining the genetic variability of asexuals through population genetic models

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F11%3A00368204" target="_blank" >RIV/60077344:_____/11:00368204 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985904:_____/11:00368204 RIV/61988987:17310/11:A12011LK

Výsledek na webu

<a href="http://dx.doi.org/10.1186/1745-6150-6-17" target="_blank" >http://dx.doi.org/10.1186/1745-6150-6-17</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/1745-6150-6-17" target="_blank" >10.1186/1745-6150-6-17</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Do clones degenerate over time? Explaining the genetic variability of asexuals through population genetic models

Popis výsledku v původním jazyce

Background: Quest for understanding the nature of mechanisms governing the life span of clonal organisms lasts for several decades. Phylogenetic evidence for recent origins of most clones is usually interpreted as proof that clones suffer from gradual age-dependent fitness decay (e.g. Muller's ratchet). However, we have shown that a neutral drift can also qualitatively explain the observed distribution of clonal ages. This finding was followed by several attempts to distinguish the effects of neutral and non-neutral processes. Most recently, Neiman et al. 2009 (Ann N Y Acad Sci.: 1168:185-200.) reviewed the distribution of asexual lineage ages estimated from a diverse array of taxa and concluded that neutral processes alone may not explain the observeddata. Moreover, the authors inferred that similar types of mechanisms determine maximum asexual lineage ages in all asexual taxa.

Název v anglickém jazyce

Do clones degenerate over time? Explaining the genetic variability of asexuals through population genetic models

Popis výsledku anglicky

Background: Quest for understanding the nature of mechanisms governing the life span of clonal organisms lasts for several decades. Phylogenetic evidence for recent origins of most clones is usually interpreted as proof that clones suffer from gradual age-dependent fitness decay (e.g. Muller's ratchet). However, we have shown that a neutral drift can also qualitatively explain the observed distribution of clonal ages. This finding was followed by several attempts to distinguish the effects of neutral and non-neutral processes. Most recently, Neiman et al. 2009 (Ann N Y Acad Sci.: 1168:185-200.) reviewed the distribution of asexual lineage ages estimated from a diverse array of taxa and concluded that neutral processes alone may not explain the observeddata. Moreover, the authors inferred that similar types of mechanisms determine maximum asexual lineage ages in all asexual taxa.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biology Direct

ISSN

1745-6150

e-ISSN

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Svazek periodika

6

Číslo periodika v rámci svazku

17

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

25

Strana od-do

1-25

Kód UT WoS článku

000288783800001

EID výsledku v databázi Scopus

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