Life cycle of Cryptosporidium muris in two rodents with different responses to parasitization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F14%3A00429422" target="_blank" >RIV/60077344:_____/14:00429422 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16170/14:43872692

Výsledek na webu

<a href="http://dx.doi.org/10.1017/S0031182013001637" target="_blank" >http://dx.doi.org/10.1017/S0031182013001637</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1017/S0031182013001637" target="_blank" >10.1017/S0031182013001637</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Life cycle of Cryptosporidium muris in two rodents with different responses to parasitization

Popis výsledku v původním jazyce

This study focuses on mapping the life cycle of Cryptosporidium muris in two laboratory rodents; BALB/c mice and the southern multimammate rat Mastomys coucha, differing in their prepatent and patent periods. Both rodents were simultaneously experimentally inoculated with viable oocysts of C. muris (strain TS03). Animals were dissected and screened for the presence of the parasite using a combined morphological approach and nested PCR (SSU rRNA) at different times after inoculation. The occurrence of first developmental stages of C. muris in stomach was detected at 2 center dot 5 days post-infection (dpi). The presence of Type II merogony, appearing 36h later than Type I merogony, was confirmed in both rodents. Oocysts exhibiting different size and thickness of their wall were observed from 5dpi onwards in stomachs of both host models. The early phase of parasitization in BALB/c mice progressed rapidly, with a prepatent period of 7 center dot 5-10 days; whereas in M. coucha, the develo

Název v anglickém jazyce

Life cycle of Cryptosporidium muris in two rodents with different responses to parasitization

Popis výsledku anglicky

This study focuses on mapping the life cycle of Cryptosporidium muris in two laboratory rodents; BALB/c mice and the southern multimammate rat Mastomys coucha, differing in their prepatent and patent periods. Both rodents were simultaneously experimentally inoculated with viable oocysts of C. muris (strain TS03). Animals were dissected and screened for the presence of the parasite using a combined morphological approach and nested PCR (SSU rRNA) at different times after inoculation. The occurrence of first developmental stages of C. muris in stomach was detected at 2 center dot 5 days post-infection (dpi). The presence of Type II merogony, appearing 36h later than Type I merogony, was confirmed in both rodents. Oocysts exhibiting different size and thickness of their wall were observed from 5dpi onwards in stomachs of both host models. The early phase of parasitization in BALB/c mice progressed rapidly, with a prepatent period of 7 center dot 5-10 days; whereas in M. coucha, the develo

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Parasitology

ISSN

0031-1820

e-ISSN

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Svazek periodika

141

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

17

Strana od-do

287-303

Kód UT WoS článku

000331903700013

EID výsledku v databázi Scopus

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