(Self-) infections with parasites: re-interpretations for the present

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F14%3A00435095" target="_blank" >RIV/60077344:_____/14:00435095 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12310/14:43887210

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.pt.2014.06.005" target="_blank" >http://dx.doi.org/10.1016/j.pt.2014.06.005</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.pt.2014.06.005" target="_blank" >10.1016/j.pt.2014.06.005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

(Self-) infections with parasites: re-interpretations for the present

Popis výsledku v původním jazyce

Previously, scientists sometimes resorted to infecting themselves or colleagues with parasites, usually to assess the pathogenicity and obtain insight into the life cycles of the parasites, host specificity, and epidemiology. However, with recent research addressing the possible beneficial impact of intestinal helminths on a range of immune-mediated diseases in humans, these studies offer valuable information, although many are now considered unethical owing to a lack of experimental oversight and informed consent. Here, we critically review cases in which humans were deliberately infected with parasites. Moreover, we summarize the contribution of (self-) infections and propose protist and helminth candidates, chosen on the basis of several criteria, to test as possible therapy for selected human diseases.

Název v anglickém jazyce

(Self-) infections with parasites: re-interpretations for the present

Popis výsledku anglicky

Previously, scientists sometimes resorted to infecting themselves or colleagues with parasites, usually to assess the pathogenicity and obtain insight into the life cycles of the parasites, host specificity, and epidemiology. However, with recent research addressing the possible beneficial impact of intestinal helminths on a range of immune-mediated diseases in humans, these studies offer valuable information, although many are now considered unethical owing to a lack of experimental oversight and informed consent. Here, we critically review cases in which humans were deliberately infected with parasites. Moreover, we summarize the contribution of (self-) infections and propose protist and helminth candidates, chosen on the basis of several criteria, to test as possible therapy for selected human diseases.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EG - Zoologie

OECD FORD obor

—

Projekt

<a href="/cs/project/GAP506%2F12%2F1632" target="_blank" >GAP506/12/1632: Od ryby k člověku a z vody na zem: evoluce tasemnic tetrapodů (Cestoda: Diphyllobothriidea)</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Trends in Parasitology

ISSN

1471-4922

e-ISSN

—

Svazek periodika

30

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

377-385

Kód UT WoS článku

000340305300004

EID výsledku v databázi Scopus

—