Unexpectedly Streamlined Mitochondrial Genome of the Euglenozoan Euglena gracilis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F15%3A00453259" target="_blank" >RIV/60077344:_____/15:00453259 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12310/15:43889381

Výsledek na webu

<a href="http://dx.doi.org/10.1093/gbe/evv229" target="_blank" >http://dx.doi.org/10.1093/gbe/evv229</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/gbe/evv229" target="_blank" >10.1093/gbe/evv229</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Unexpectedly Streamlined Mitochondrial Genome of the Euglenozoan Euglena gracilis

Popis výsledku v původním jazyce

In this study, we describe the mitochondrial genome of the excavate flagellate Euglena gracilis. Its gene complement is reduced as compared with the well-studied sister groups Diplonemea and Kinetoplastea.We have identified seven protein-coding genes: Three subunits of respiratory complex I (nad1, nad4, and nad5), one subunit of complex III (cob), and three subunits of complex IV (cox1, cox2, and a highly divergent cox3).Moreover, fragments of ribosomalRNAgenes have also been identified.Genes encoding subunits of complex V, ribosomal proteins and tRNAs were missing, and are likely located in the nuclear genome. Although mitochondrial genomes of diplonemids and kinetoplastids possess themost complex RNA processingmachineries known, including trans-splicing and editing of the uridine insertion/deletion type, respectively, our transcriptomic data suggest their total absence in E. gracilis. This finding supports a scenario inwhich the complexmitochondrial processingmachineries of

Název v anglickém jazyce

Unexpectedly Streamlined Mitochondrial Genome of the Euglenozoan Euglena gracilis

Popis výsledku anglicky

In this study, we describe the mitochondrial genome of the excavate flagellate Euglena gracilis. Its gene complement is reduced as compared with the well-studied sister groups Diplonemea and Kinetoplastea.We have identified seven protein-coding genes: Three subunits of respiratory complex I (nad1, nad4, and nad5), one subunit of complex III (cob), and three subunits of complex IV (cox1, cox2, and a highly divergent cox3).Moreover, fragments of ribosomalRNAgenes have also been identified.Genes encoding subunits of complex V, ribosomal proteins and tRNAs were missing, and are likely located in the nuclear genome. Although mitochondrial genomes of diplonemids and kinetoplastids possess themost complex RNA processingmachineries known, including trans-splicing and editing of the uridine insertion/deletion type, respectively, our transcriptomic data suggest their total absence in E. gracilis. This finding supports a scenario inwhich the complexmitochondrial processingmachineries of

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA15-21974S" target="_blank" >GA15-21974S: Studium vztahů mezi RNA-vážícími bílkovinami a mitochondriálním genomem trypanosom</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Genome Biology and Evolution

ISSN

1759-6653

e-ISSN

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Svazek periodika

7

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

3358-3367

Kód UT WoS článku

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EID výsledku v databázi Scopus

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