Modulation of host immunity by tick saliva

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F15%3A00453381" target="_blank" >RIV/60077344:_____/15:00453381 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12310/15:43890250

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jprot.2015.07.005" target="_blank" >http://dx.doi.org/10.1016/j.jprot.2015.07.005</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jprot.2015.07.005" target="_blank" >10.1016/j.jprot.2015.07.005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Modulation of host immunity by tick saliva

Popis výsledku v původním jazyce

Next generation sequencing and proteomics have helped to comprehensively characterize gene expression in tick salivary glands at both the transcriptome and the proteome level. Functional data are, however, lacking. Given that tick salivary secretions arecritical to the success of the tick transmission lifecycle and, as a consequence, for host colonization by the pathogens they spread, we thoroughly review here the literature on the known interactions between tick saliva (or tick salivary gland extracts) and the innate and adaptive vertebrate immune system. The information is intended to serve as a reference for functional characterization of the numerous genes and proteins expressed in tick salivary glands with an ultimate goal to develop novel vectorand pathogen control strategies. /nSignificance: We overview all the known interactions of tick saliva with the vertebrate immune system. The provided information is important, given the recent developments in high-throughput transcripto

Název v anglickém jazyce

Modulation of host immunity by tick saliva

Popis výsledku anglicky

Next generation sequencing and proteomics have helped to comprehensively characterize gene expression in tick salivary glands at both the transcriptome and the proteome level. Functional data are, however, lacking. Given that tick salivary secretions arecritical to the success of the tick transmission lifecycle and, as a consequence, for host colonization by the pathogens they spread, we thoroughly review here the literature on the known interactions between tick saliva (or tick salivary gland extracts) and the innate and adaptive vertebrate immune system. The information is intended to serve as a reference for functional characterization of the numerous genes and proteins expressed in tick salivary glands with an ultimate goal to develop novel vectorand pathogen control strategies. /nSignificance: We overview all the known interactions of tick saliva with the vertebrate immune system. The provided information is important, given the recent developments in high-throughput transcripto

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/GAP502%2F12%2F2409" target="_blank" >GAP502/12/2409: Úloha inhibitorů proteáz z klíštěcích slin v interakcích mezi klíšťaty, patogeny a hostitelem</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Proteomics

ISSN

1874-3919

e-ISSN

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Svazek periodika

128

Číslo periodika v rámci svazku

OCT 14 2015

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

58-68

Kód UT WoS článku

000364882200006

EID výsledku v databázi Scopus

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