Phytotoxicity of acyclic nucleoside phosphonates in Brassica pekinensis and Solanum lycopersicum

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F16%3A00460505" target="_blank" >RIV/60077344:_____/16:00460505 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61388963:_____/16:00460505

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s11240-016-0942-4" target="_blank" >http://dx.doi.org/10.1007/s11240-016-0942-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11240-016-0942-4" target="_blank" >10.1007/s11240-016-0942-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Phytotoxicity of acyclic nucleoside phosphonates in Brassica pekinensis and Solanum lycopersicum

Popis výsledku v původním jazyce

Phytotoxicity of acyclic nucleoside phosphonates (ANPs), namely (R)-PMPA, (S)-PMPA, (S)-PMPG, (S)-HPMPO-DAPy, N (6)-cPr-PMEDAP, (S)-HPMPC, PMEDAP, (S)-FPMPA, N (6)-furfuryl-PMEA, (S)-HPMPA, PMEG, (R)-PMPDAP, PMEO-DAPy, (R,S)-2'-CF3-PMEDAP, (R)-8-PMP-8-azaA, and (R)-PMP-3-deazaA, comprising potential antiviral agents against plant DNA viruses, was tested in whole plants of Brassica pekinensis and Solanum lycopersicum cultivated for 6 weeks in vitro on Murashige and Skoog liquid medium containing individual ANPs at concentrations 12.5 and 25 mg/L. Statistical analysis revealed significant reduction (P < 0.05) in fresh weight of B. pekinensis treated with 12.5 mg/L and 25 mg/L of N (6)-cPr-PMEDAP, (S)-HPMPC, PMEDAP, (S)-FPMPA, and PMEG. Similarly, in S. lycopersicum treated with 25 mg/L of ANPs, significant reduction was observed in the cases of (S)-HPMPC, PMEDAP, (S)-FPMPA, PMEG, and (R)-PMP-3-deazaA in comparison with the plants untreated with ANPs. Dry weight of B. pekinensis treated with 12.5 mg/L was significantly reduced by (S)-HPMPC, PMEDAP and PMEG, while 25 mg/L led to significant reduction also by (S)-FPMPA and (R,S)-2'-CF3-PMEDAP. In S. lycopersicum treated with 25 mg/L, significant reduction was observed with (S)-HPMPC, PMEDAP, (S)-FPMPA, PMEG, (R,S)-2'-CF3-PMEDAP, (R)-8-PMP-8-azaA, and (R)-PMP-3-deazaA. We conclude that the identical response of S. lycopersicum and B. pekinensis to (S)-HPMPC, PMEDAP, (S)-FPMPA and PMEG allows some generalization of ANPs' effects on plants and preselection of prospective compounds for testing as to their antiviral activity.

Název v anglickém jazyce

Phytotoxicity of acyclic nucleoside phosphonates in Brassica pekinensis and Solanum lycopersicum

Popis výsledku anglicky

Phytotoxicity of acyclic nucleoside phosphonates (ANPs), namely (R)-PMPA, (S)-PMPA, (S)-PMPG, (S)-HPMPO-DAPy, N (6)-cPr-PMEDAP, (S)-HPMPC, PMEDAP, (S)-FPMPA, N (6)-furfuryl-PMEA, (S)-HPMPA, PMEG, (R)-PMPDAP, PMEO-DAPy, (R,S)-2'-CF3-PMEDAP, (R)-8-PMP-8-azaA, and (R)-PMP-3-deazaA, comprising potential antiviral agents against plant DNA viruses, was tested in whole plants of Brassica pekinensis and Solanum lycopersicum cultivated for 6 weeks in vitro on Murashige and Skoog liquid medium containing individual ANPs at concentrations 12.5 and 25 mg/L. Statistical analysis revealed significant reduction (P < 0.05) in fresh weight of B. pekinensis treated with 12.5 mg/L and 25 mg/L of N (6)-cPr-PMEDAP, (S)-HPMPC, PMEDAP, (S)-FPMPA, and PMEG. Similarly, in S. lycopersicum treated with 25 mg/L of ANPs, significant reduction was observed in the cases of (S)-HPMPC, PMEDAP, (S)-FPMPA, PMEG, and (R)-PMP-3-deazaA in comparison with the plants untreated with ANPs. Dry weight of B. pekinensis treated with 12.5 mg/L was significantly reduced by (S)-HPMPC, PMEDAP and PMEG, while 25 mg/L led to significant reduction also by (S)-FPMPA and (R,S)-2'-CF3-PMEDAP. In S. lycopersicum treated with 25 mg/L, significant reduction was observed with (S)-HPMPC, PMEDAP, (S)-FPMPA, PMEG, (R,S)-2'-CF3-PMEDAP, (R)-8-PMP-8-azaA, and (R)-PMP-3-deazaA. We conclude that the identical response of S. lycopersicum and B. pekinensis to (S)-HPMPC, PMEDAP, (S)-FPMPA and PMEG allows some generalization of ANPs' effects on plants and preselection of prospective compounds for testing as to their antiviral activity.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EE - Mikrobiologie, virologie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Plant Cell, Tissue and Organ Culture

ISSN

0167-6857

e-ISSN

—

Svazek periodika

125

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

5

Strana od-do

375-379

Kód UT WoS článku

000374593400017

EID výsledku v databázi Scopus

2-s2.0-84953404643