Fabrication and bioapplications of magnetically modified chitosan-based electrospun nanofibers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F18%3A00494580" target="_blank" >RIV/60077344:_____/18:00494580 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15310/18:73590908

Výsledek na webu

<a href="http://dx.doi.org/10.1515/esp-2018-0003" target="_blank" >http://dx.doi.org/10.1515/esp-2018-0003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/esp-2018-0003" target="_blank" >10.1515/esp-2018-0003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fabrication and bioapplications of magnetically modified chitosan-based electrospun nanofibers

Popis výsledku v původním jazyce

The fabrication of magnetically modified electrospun nanocomposite fibers based on a naturallyderived biocompatible and biodegradable polysaccharide chitosan (CS) and the hydrophilic and biocompatible poly(vinylpyrrolidone) (PVP) is reported herein. The anchoring of magnetic nanoparticles (MNPs) onto the surfaces of the electrospun PVP/CS fibers was carried out by a post-magnetization process based on chemical coprecipitation, via immersing the produced fibrous mats in an aqueous solution containing Fe(II) and Fe(III) salts at appropriate molar ratios, followed by the addition of a weak base to yield MNPs. Electron microscopy revealed the presence of continuous micron and submicron fibers surface-decorated with MNPs. The magnetically modified PVP/CS fibers exhibited superparamagnetic behavior at ambient temperature. The magnetic fibrous nanocomposite carrier was employed for the immobilization of Saccharomyces cerevisiae cells and their use for sucrose hydrolysis, and Candida rugosa lipase and its use for artificial substrate hydrolysis.

Název v anglickém jazyce

Fabrication and bioapplications of magnetically modified chitosan-based electrospun nanofibers

Popis výsledku anglicky

The fabrication of magnetically modified electrospun nanocomposite fibers based on a naturallyderived biocompatible and biodegradable polysaccharide chitosan (CS) and the hydrophilic and biocompatible poly(vinylpyrrolidone) (PVP) is reported herein. The anchoring of magnetic nanoparticles (MNPs) onto the surfaces of the electrospun PVP/CS fibers was carried out by a post-magnetization process based on chemical coprecipitation, via immersing the produced fibrous mats in an aqueous solution containing Fe(II) and Fe(III) salts at appropriate molar ratios, followed by the addition of a weak base to yield MNPs. Electron microscopy revealed the presence of continuous micron and submicron fibers surface-decorated with MNPs. The magnetically modified PVP/CS fibers exhibited superparamagnetic behavior at ambient temperature. The magnetic fibrous nanocomposite carrier was employed for the immobilization of Saccharomyces cerevisiae cells and their use for sucrose hydrolysis, and Candida rugosa lipase and its use for artificial substrate hydrolysis.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

<a href="/cs/project/LO1305" target="_blank" >LO1305: Rozvoj centra pokročilých technologií a materiálů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electrospinning

ISSN

2391-7407

e-ISSN

—

Svazek periodika

2

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

11

Strana od-do

29-39

Kód UT WoS článku

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EID výsledku v databázi Scopus

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