Autophagy and apoptosis in the midgut epithelium of millipedes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F19%3A00507550" target="_blank" >RIV/60077344:_____/19:00507550 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/19:10399874

Výsledek na webu

<a href="https://www.cambridge.org/core/services/aop-cambridge-core/content/view/563245508CCC638A2268E992737C5961/S143192761900059Xa.pdf/div-class-title-autophagy-and-apoptosis-in-the-midgut-epithelium-of-millipedes-div.pdf" target="_blank" >https://www.cambridge.org/core/services/aop-cambridge-core/content/view/563245508CCC638A2268E992737C5961/S143192761900059Xa.pdf/div-class-title-autophagy-and-apoptosis-in-the-midgut-epithelium-of-millipedes-div.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1017/S143192761900059X" target="_blank" >10.1017/S143192761900059X</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Autophagy and apoptosis in the midgut epithelium of millipedes

Popis výsledku v původním jazyce

The process of autophagy has been detected in the midgut epithelium of four millipede species: Julus scandinavius, Polyxenus lagurus, Archispirostreptus gigas, and Telodeinopus aoutii. It has been examined using transmission electron microscopy (TEM), which enabled differentiation of cells in the midgut epithelium, and some histochemical methods (light microscope and fluorescence microscope). While autophagy appeared in the cytoplasm of digestive, secretory, and regenerative cells in J. scandinavius and A. gigas, in the two other species, T. aoutii and P. lagurus, it was only detected in the digestive cells. Both types of macroautophagy, the selective and nonselective processes, are described using TEM. Phagophore formation appeared as the first step of autophagy. After its blind ends fusion, the autophagosomes were formed. The autophagosomes fused with lysosomes and were transformed into autolysosomes. As the final step of autophagy, the residual bodies were detected. Autophagic structures can be removed from the midgut epithelium via, e.g., atypical exocytosis. Additionally, in P. lagurus and J. scandinavius, it was observed as the neutralization of pathogens such as Rickettsia-like microorganisms. Autophagy and apoptosis ca be analyzed using TEM, while specific histochemical methods may confirm it.

Název v anglickém jazyce

Autophagy and apoptosis in the midgut epithelium of millipedes

Popis výsledku anglicky

The process of autophagy has been detected in the midgut epithelium of four millipede species: Julus scandinavius, Polyxenus lagurus, Archispirostreptus gigas, and Telodeinopus aoutii. It has been examined using transmission electron microscopy (TEM), which enabled differentiation of cells in the midgut epithelium, and some histochemical methods (light microscope and fluorescence microscope). While autophagy appeared in the cytoplasm of digestive, secretory, and regenerative cells in J. scandinavius and A. gigas, in the two other species, T. aoutii and P. lagurus, it was only detected in the digestive cells. Both types of macroautophagy, the selective and nonselective processes, are described using TEM. Phagophore formation appeared as the first step of autophagy. After its blind ends fusion, the autophagosomes were formed. The autophagosomes fused with lysosomes and were transformed into autolysosomes. As the final step of autophagy, the residual bodies were detected. Autophagic structures can be removed from the midgut epithelium via, e.g., atypical exocytosis. Additionally, in P. lagurus and J. scandinavius, it was observed as the neutralization of pathogens such as Rickettsia-like microorganisms. Autophagy and apoptosis ca be analyzed using TEM, while specific histochemical methods may confirm it.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10613 - Zoology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Microscopy and Microanalysis

ISSN

1431-9276

e-ISSN

—

Svazek periodika

25

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

13

Strana od-do

1004-1016

Kód UT WoS článku

000485052600019

EID výsledku v databázi Scopus

2-s2.0-85065912638