Diverse alveolate infections of tadpoles, a new threat to frogs?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F20%3A00538253" target="_blank" >RIV/60077344:_____/20:00538253 - isvavai.cz</a>

Výsledek na webu

<a href="https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008107" target="_blank" >https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008107</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1371/journal.ppat.1008107" target="_blank" >10.1371/journal.ppat.1008107</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Diverse alveolate infections of tadpoles, a new threat to frogs?

Popis výsledku v původním jazyce

The research summarized here demonstrates a range of alveolate infections of specific tadpole tissues and cell types critical for immune function and core physiology. The severe Perkinsozoa-infection etiologic agent associated with mass mortality events across the USA is now considered an emerging infection [16] and lies within a particular alveolate clade sampled from freshwater environments and tadpole tissues. We need to know how deterministic these infections are, either individually or in concert with other microbes and/or environmental factors, and the epizootiology of the disease. For example, environmental factors, such as pollution, can create sublethal stress resulting in suppression of the immune function, leading to an increase of disease susceptibility. As such, we need to apply an approach that allows the investigation of disease progression concordant with formal tests of Koch’s postulates [7]. We also need to know how virulence, if present, varies among different amphibian-associated perkinsozoans and apicomplexans.

Název v anglickém jazyce

Diverse alveolate infections of tadpoles, a new threat to frogs?

Popis výsledku anglicky

The research summarized here demonstrates a range of alveolate infections of specific tadpole tissues and cell types critical for immune function and core physiology. The severe Perkinsozoa-infection etiologic agent associated with mass mortality events across the USA is now considered an emerging infection [16] and lies within a particular alveolate clade sampled from freshwater environments and tadpole tissues. We need to know how deterministic these infections are, either individually or in concert with other microbes and/or environmental factors, and the epizootiology of the disease. For example, environmental factors, such as pollution, can create sublethal stress resulting in suppression of the immune function, leading to an increase of disease susceptibility. As such, we need to apply an approach that allows the investigation of disease progression concordant with formal tests of Koch’s postulates [7]. We also need to know how virulence, if present, varies among different amphibian-associated perkinsozoans and apicomplexans.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/EF16_019%2F0000759" target="_blank" >EF16_019/0000759: Centrum výzkumu patogenity a virulence parazitů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PLoS Pathogens

ISSN

1553-7374

e-ISSN

—

Svazek periodika

16

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

e1008107

Kód UT WoS článku

000518637800023

EID výsledku v databázi Scopus

2-s2.0-85079334907