Ultrasound transmission tomography-guided heating with nanoparticles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F22%3A00559550" target="_blank" >RIV/60077344:_____/22:00559550 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15640/22:73618768

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0263224122005826?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0263224122005826?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.measurement.2022.111345" target="_blank" >10.1016/j.measurement.2022.111345</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ultrasound transmission tomography-guided heating with nanoparticles

Popis výsledku v původním jazyce

Nanoparticles can be used in numerous therapeutic procedures, including controlled drug delivery and release, thermal therapy, and photo- and sonodynamic therapy. However, such approaches remain limited due to difficulties associated with accurately controlling their therapeutic efficiency and localized consequences. Thus, we propose the use of ultrasound transmission tomography (UTT) measurements following ultrasonic heating when using nanomaterials as mediators. We test various nanomaterials doped to agar tissue-mimicking phantoms to study how they affect the UTT imaging through improving the contrast. Simultaneously, we investigate the suitability of these mediators in relation to the process of ultrasonic heating under the guidance of UTT. The results show that UTT is sensitive to the presence of magnetic nanoparticle-based nanomaterials and induced temperature rises. The combination of an imaging modality based on generally safe and well-known ultrasound-based imaging and the use of nanomaterials as mediators represents our proposal for a new theranostic approach.

Název v anglickém jazyce

Ultrasound transmission tomography-guided heating with nanoparticles

Popis výsledku anglicky

Nanoparticles can be used in numerous therapeutic procedures, including controlled drug delivery and release, thermal therapy, and photo- and sonodynamic therapy. However, such approaches remain limited due to difficulties associated with accurately controlling their therapeutic efficiency and localized consequences. Thus, we propose the use of ultrasound transmission tomography (UTT) measurements following ultrasonic heating when using nanomaterials as mediators. We test various nanomaterials doped to agar tissue-mimicking phantoms to study how they affect the UTT imaging through improving the contrast. Simultaneously, we investigate the suitability of these mediators in relation to the process of ultrasonic heating under the guidance of UTT. The results show that UTT is sensitive to the presence of magnetic nanoparticle-based nanomaterials and induced temperature rises. The combination of an imaging modality based on generally safe and well-known ultrasound-based imaging and the use of nanomaterials as mediators represents our proposal for a new theranostic approach.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10307 - Acoustics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Measurement

ISSN

0263-2241

e-ISSN

1873-412X

Svazek periodika

197

Číslo periodika v rámci svazku

June

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

15

Strana od-do

111345

Kód UT WoS článku

000882954400005

EID výsledku v databázi Scopus

2-s2.0-85133903544