Leishmania tarentolae: A new frontier in the epidemiology and control of the leishmaniases

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F22%3A00561825" target="_blank" >RIV/60077344:_____/22:00561825 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/22:10450693 RIV/00216224:14310/22:00128125 RIV/60460709:41210/22:92377

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/10.1111/tbed.14660" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/tbed.14660</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/tbed.14660" target="_blank" >10.1111/tbed.14660</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Leishmania tarentolae: A new frontier in the epidemiology and control of the leishmaniases

Popis výsledku v původním jazyce

Leishmaniasis (or the leishmaniases), classified as a neglected tropical parasitic disease, is found in parts of the tropics, subtropics and southern Europe. Leishmania parasites are transmitted by the bite of phlebotomine sand flies and million cases of human infection occur annually. Leishmania tarentolae has been historically considered a non-pathogenic protozoan of reptiles, which has been studied mainly for its potential biotechnological applications. However, some strains of L. tarentolae appear to be transiently infective to mammals. In areas where leishmaniasis is endemic, recent molecular diagnostics and serological positivity to L. tarentolae in humans and dogs have spurred interest in the interactions between these mammalian hosts, reptiles and Leishmania infantum, the main aetiologic agent of human and canine leishmaniasis. In this review, we discuss the systematics and biology of L. tarentolae in the insect vectors and the vertebrate hosts and address questions about evolution of reptilian leishmaniae. Furthermore, we discuss the possible usefulness of L. tarentolae for new vaccination strategies.

Název v anglickém jazyce

Leishmania tarentolae: A new frontier in the epidemiology and control of the leishmaniases

Popis výsledku anglicky

Leishmaniasis (or the leishmaniases), classified as a neglected tropical parasitic disease, is found in parts of the tropics, subtropics and southern Europe. Leishmania parasites are transmitted by the bite of phlebotomine sand flies and million cases of human infection occur annually. Leishmania tarentolae has been historically considered a non-pathogenic protozoan of reptiles, which has been studied mainly for its potential biotechnological applications. However, some strains of L. tarentolae appear to be transiently infective to mammals. In areas where leishmaniasis is endemic, recent molecular diagnostics and serological positivity to L. tarentolae in humans and dogs have spurred interest in the interactions between these mammalian hosts, reptiles and Leishmania infantum, the main aetiologic agent of human and canine leishmaniasis. In this review, we discuss the systematics and biology of L. tarentolae in the insect vectors and the vertebrate hosts and address questions about evolution of reptilian leishmaniae. Furthermore, we discuss the possible usefulness of L. tarentolae for new vaccination strategies.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/EF16_019%2F0000759" target="_blank" >EF16_019/0000759: Centrum výzkumu patogenity a virulence parazitů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Transboundary and Emerging Diseases

ISSN

1865-1674

e-ISSN

1865-1682

Svazek periodika

69

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

12

Strana od-do

"E1326"-"E1337"

Kód UT WoS článku

000835254800001

EID výsledku v databázi Scopus

2-s2.0-85135207494