Evolution of RNA viruses in trypanosomatids: new insights from the analysis of Sauroleishmania

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00576092" target="_blank" >RIV/60077344:_____/23:00576092 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17310/23:A2402MI4 RIV/00216224:14740/23:00131575 RIV/00216208:11310/23:10469353

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s00436-023-07928-x" target="_blank" >https://link.springer.com/article/10.1007/s00436-023-07928-x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00436-023-07928-x" target="_blank" >10.1007/s00436-023-07928-x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Evolution of RNA viruses in trypanosomatids: new insights from the analysis of Sauroleishmania

Popis výsledku v původním jazyce

RNA viruses play an important role in Leishmania biology and virulence. Their presence was documented in three (out of four) Leishmania subgenera. Sauroleishmania of reptiles remained the only underinvestigated group. In this work, we analyzed the viral occurrence in Sauroleishmania spp. and detected RNA viruses in three out of seven isolates under study. These viruses were of two families-Narnaviridae and Totiviridae. Phylogenetic inferences demonstrated that totiviruses from L. adleri and L. tarentolae group together within a larger cluster of LRV2s, while a narnavirus of L. gymnodactyli appeared as a phylogenetic relative of narnaviruses of Blechomonas spp. Taken together, our work not only expanded the range of trypanosomatids that can host RNA viruses but also shed new light on the evolution and potential routes of viral transmission in these flagellates.

Název v anglickém jazyce

Evolution of RNA viruses in trypanosomatids: new insights from the analysis of Sauroleishmania

Popis výsledku anglicky

RNA viruses play an important role in Leishmania biology and virulence. Their presence was documented in three (out of four) Leishmania subgenera. Sauroleishmania of reptiles remained the only underinvestigated group. In this work, we analyzed the viral occurrence in Sauroleishmania spp. and detected RNA viruses in three out of seven isolates under study. These viruses were of two families-Narnaviridae and Totiviridae. Phylogenetic inferences demonstrated that totiviruses from L. adleri and L. tarentolae group together within a larger cluster of LRV2s, while a narnavirus of L. gymnodactyli appeared as a phylogenetic relative of narnaviruses of Blechomonas spp. Taken together, our work not only expanded the range of trypanosomatids that can host RNA viruses but also shed new light on the evolution and potential routes of viral transmission in these flagellates.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Parasitology Research

ISSN

0932-0113

e-ISSN

1432-1955

Svazek periodika

122

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

8

Strana od-do

2279-2286

Kód UT WoS článku

001035484700001

EID výsledku v databázi Scopus

2-s2.0-85165715334