Trypanosomes as a magnifying glass for cell and molecular biology

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00579778" target="_blank" >RIV/60077344:_____/23:00579778 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12310/23:43906681

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1471492223001952?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1471492223001952?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.pt.2023.08.004" target="_blank" >10.1016/j.pt.2023.08.004</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Trypanosomes as a magnifying glass for cell and molecular biology

Popis výsledku v původním jazyce

The African trypanosome, Trypanosoma brucei, has developed into a flexible and robust experimental model for molecular and cellular parasitology, allowing us to better combat these and related parasites that cause worldwide suffering. Diminishing case numbers, due to efficient public health efforts, and recent de-velopment of new drug treatments have reduced the need for continued study of T. brucei in a disease context. However, we argue that this pathogen has been instrumental in revolutionary discoveries that have widely informed molec-ular and cellular biology and justifies continuing research as an experimental model. Ongoing work continues to contribute towards greater understanding of both diversified and conserved biological features. We discuss multiple examples where trypanosomes pushed the boundaries of cell biology and hope to inspire researchers to continue exploring these remarkable protists as tools for magnifying the inner workings of cells.

Název v anglickém jazyce

Trypanosomes as a magnifying glass for cell and molecular biology

Popis výsledku anglicky

The African trypanosome, Trypanosoma brucei, has developed into a flexible and robust experimental model for molecular and cellular parasitology, allowing us to better combat these and related parasites that cause worldwide suffering. Diminishing case numbers, due to efficient public health efforts, and recent de-velopment of new drug treatments have reduced the need for continued study of T. brucei in a disease context. However, we argue that this pathogen has been instrumental in revolutionary discoveries that have widely informed molec-ular and cellular biology and justifies continuing research as an experimental model. Ongoing work continues to contribute towards greater understanding of both diversified and conserved biological features. We discuss multiple examples where trypanosomes pushed the boundaries of cell biology and hope to inspire researchers to continue exploring these remarkable protists as tools for magnifying the inner workings of cells.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Trends in Parasitology

ISSN

1471-4922

e-ISSN

1471-5007

Svazek periodika

39

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

902-912

Kód UT WoS článku

001099395600001

EID výsledku v databázi Scopus

2-s2.0-85169898897