Viroids: Non-coding Circular RNAs Are Tiny Pathogens Provoking a Broad Response in Host Plants

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F23%3A00584519" target="_blank" >RIV/60077344:_____/23:00584519 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/chapter/10.1007/978-3-031-36390-0_14" target="_blank" >https://link.springer.com/chapter/10.1007/978-3-031-36390-0_14</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Viroids: Non-coding Circular RNAs Are Tiny Pathogens Provoking a Broad Response in Host Plants

Popis výsledku v původním jazyce

More than 50 years ago, viroids were firstly described as the smallest RNA molecules capable to infect certain plants and to autonomously self-replicate in host plants. Viroids are covalently closed circular single-stranded RNAs that are non-coding and depend for most of their infection cycle on host proteins. Today, viroids are subdivided into the two families Avsunviroidae and Pospiviroidae. Members of Avsunviroidae replicate in the chloroplast and have a highly bifurcated structure including hammerhead ribozymes, which cleave oligomeric replication intermediates into monomers and ligate them to mature circles. Members of Pospiviroidae accumulate in the nucleus, have a rod-like structure and depend on host proteins for cleavage and ligation. We will describe our present knowledge on sequence and structural elements of viroids in connection to their replication and trafficking.

Název v anglickém jazyce

Viroids: Non-coding Circular RNAs Are Tiny Pathogens Provoking a Broad Response in Host Plants

Popis výsledku anglicky

More than 50 years ago, viroids were firstly described as the smallest RNA molecules capable to infect certain plants and to autonomously self-replicate in host plants. Viroids are covalently closed circular single-stranded RNAs that are non-coding and depend for most of their infection cycle on host proteins. Today, viroids are subdivided into the two families Avsunviroidae and Pospiviroidae. Members of Avsunviroidae replicate in the chloroplast and have a highly bifurcated structure including hammerhead ribozymes, which cleave oligomeric replication intermediates into monomers and ligate them to mature circles. Members of Pospiviroidae accumulate in the nucleus, have a rod-like structure and depend on host proteins for cleavage and ligation. We will describe our present knowledge on sequence and structural elements of viroids in connection to their replication and trafficking.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10607 - Virology

Projekt

<a href="/cs/project/GC18-10515J" target="_blank" >GC18-10515J: Mechanismus propagace a eliminace parazitické RNA u samčí zárodečné linie při studiu u hospodářsky významného druhu viroidu.</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů