Strongyloides in non-human primates: significance for public health control

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00580710" target="_blank" >RIV/60077344:_____/24:00580710 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081766:_____/24:00580399 RIV/60460709:41210/24:98596 RIV/00216224:14310/24:00135287

Výsledek na webu

<a href="https://royalsocietypublishing.org/doi/10.1098/rstb.2023.0006" target="_blank" >https://royalsocietypublishing.org/doi/10.1098/rstb.2023.0006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1098/rstb.2023.0006" target="_blank" >10.1098/rstb.2023.0006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Strongyloides in non-human primates: significance for public health control

Popis výsledku v původním jazyce

Primates are an important source of infectious disease in humans. Strongyloidiasis affects an estimated 600 million people worldwide, with a global distribution and hotspots of infection in tropical and subtropical regions. Recently added to the list of neglected tropical diseases, global attention has been demanded in the drive for its control. Through a literature review of Strongyloides in humans and non-human primates (NHP), we analysed the most common identification methods and gaps in knowledge about this nematode genus. The rise of molecular-based methods for Strongyloides detection is evident in both humans and NHP and provides an opportunity to analyse all data available from primates. Dogs were also included as an important host species of Strongyloides and a potential bridge host between humans and NHP. This review highlights the lack of molecular data across all hosts-humans, NHP and dogs-with the latter highly underrepresented in the database. Despite the cosmopolitan nature of Strongyloides, there are still large gaps in our knowledge for certain species when considering transmission and pathogenicity. We suggest that a unified approach to Strongyloides detection be taken, with an optimized, repeatable molecular-based method to improve our understanding of this parasitic infection.This article is part of the Theo Murphy meeting issue 'Strongyloides: omics to worm-free populations'.

Název v anglickém jazyce

Strongyloides in non-human primates: significance for public health control

Popis výsledku anglicky

Primates are an important source of infectious disease in humans. Strongyloidiasis affects an estimated 600 million people worldwide, with a global distribution and hotspots of infection in tropical and subtropical regions. Recently added to the list of neglected tropical diseases, global attention has been demanded in the drive for its control. Through a literature review of Strongyloides in humans and non-human primates (NHP), we analysed the most common identification methods and gaps in knowledge about this nematode genus. The rise of molecular-based methods for Strongyloides detection is evident in both humans and NHP and provides an opportunity to analyse all data available from primates. Dogs were also included as an important host species of Strongyloides and a potential bridge host between humans and NHP. This review highlights the lack of molecular data across all hosts-humans, NHP and dogs-with the latter highly underrepresented in the database. Despite the cosmopolitan nature of Strongyloides, there are still large gaps in our knowledge for certain species when considering transmission and pathogenicity. We suggest that a unified approach to Strongyloides detection be taken, with an optimized, repeatable molecular-based method to improve our understanding of this parasitic infection.This article is part of the Theo Murphy meeting issue 'Strongyloides: omics to worm-free populations'.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30102 - Immunology

Projekt

<a href="/cs/project/GA22-16475S" target="_blank" >GA22-16475S: Gastrointestinální komunity symbiontů u lidoopů jako bioindikátory zdraví tropických ekosystémů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Philosophical Transactions of the Royal Society B-Biological Sciences

ISSN

0962-8436

e-ISSN

1471-2970

Svazek periodika

379

Číslo periodika v rámci svazku

1894

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

11

Strana od-do

20230006

Kód UT WoS článku

001124260400005

EID výsledku v databázi Scopus

2-s2.0-85177783483