It's not all about flagella sticky invasion by pathogenic spirochetes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00586751" target="_blank" >RIV/60077344:_____/24:00586751 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12310/24:43908299

Výsledek na webu

<a href="https://doi.org/10.1016/j.pt.2024.03.004" target="_blank" >https://doi.org/10.1016/j.pt.2024.03.004</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.pt.2024.03.004" target="_blank" >10.1016/j.pt.2024.03.004</a>

Jazyk výsledku

angličtina

Název v původním jazyce

It's not all about flagella sticky invasion by pathogenic spirochetes

Popis výsledku v původním jazyce

Pathogenic spirochetes cause a range of serious human diseases such as Lyme disease (LD), syphilis, leptospirosis, relapsing fever (RF), and periodontal disease. Motility is a critical virulence factor for spirochetes. From the mechanical perspective of the infection, it has been widely believed that flagella are the sole key players governing the migration and dissemination of these pathogens in the host. Here, we highlight the important contribution of spirochetal surface-exposed adhesive molecules and their dynamic interactions with host molecules in the process of infection, specifically in spirochetal swimming and crawling migration. We believe that these recent findings overturn the prevailing view depicting the spirochetal body to be just an inert elastic bag, which does not affect spirochetal cell locomotion.

Název v anglickém jazyce

It's not all about flagella sticky invasion by pathogenic spirochetes

Popis výsledku anglicky

Pathogenic spirochetes cause a range of serious human diseases such as Lyme disease (LD), syphilis, leptospirosis, relapsing fever (RF), and periodontal disease. Motility is a critical virulence factor for spirochetes. From the mechanical perspective of the infection, it has been widely believed that flagella are the sole key players governing the migration and dissemination of these pathogens in the host. Here, we highlight the important contribution of spirochetal surface-exposed adhesive molecules and their dynamic interactions with host molecules in the process of infection, specifically in spirochetal swimming and crawling migration. We believe that these recent findings overturn the prevailing view depicting the spirochetal body to be just an inert elastic bag, which does not affect spirochetal cell locomotion.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/GF22-18647K" target="_blank" >GF22-18647K: Strukturní a bio-nanomechanický pohled na diseminaci bakterií v hostiteli</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Trends in Parasitology

ISSN

1471-4922

e-ISSN

1471-5007

Svazek periodika

40

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

378-385

Kód UT WoS článku

001239119600003

EID výsledku v databázi Scopus

2-s2.0-85188727508