Inside the Host: Understanding the Evolutionary Trajectories of Intracellular Parasitism

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00603879" target="_blank" >RIV/60077344:_____/24:00603879 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17310/24:A25039VE RIV/60076658:12310/24:43908490

Výsledek na webu

<a href="https://doi.org/10.1146/annurev-micro-041222-025305" target="_blank" >https://doi.org/10.1146/annurev-micro-041222-025305</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1146/annurev-micro-041222-025305" target="_blank" >10.1146/annurev-micro-041222-025305</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Inside the Host: Understanding the Evolutionary Trajectories of Intracellular Parasitism

Popis výsledku v původním jazyce

This review explores the origins of intracellular parasitism, an intriguing facet of symbiosis, where one organism harms its host, potentially becoming deadly. We focus on three distantly related groups of single-celled eukaryotes, namely Kinetoplastea, Holomycota, and Apicomplexa, which contain multiple species-rich lineages of intracellular parasites. Using comparative analysis of morphological, physiological, and molecular features of kinetoplastids, microsporidians, and sporozoans, as well as their closest free-living relatives, we reveal the evolutionary trajectories and adaptations that enabled the transition to intracellular parasitism. Intracellular parasites have evolved various efficient mechanisms for host acquisition and exploitation, allowing them to thrive in a variety of hosts. Each group has developed unique features related to the parasitic lifestyle, involving dedicated protein families associated with host cell invasion, survival, and exit. Indeed, parallel evolution has led to distinct lineages of intracellular parasites employing diverse traits and approaches to achieve similar outcomes.

Název v anglickém jazyce

Inside the Host: Understanding the Evolutionary Trajectories of Intracellular Parasitism

Popis výsledku anglicky

This review explores the origins of intracellular parasitism, an intriguing facet of symbiosis, where one organism harms its host, potentially becoming deadly. We focus on three distantly related groups of single-celled eukaryotes, namely Kinetoplastea, Holomycota, and Apicomplexa, which contain multiple species-rich lineages of intracellular parasites. Using comparative analysis of morphological, physiological, and molecular features of kinetoplastids, microsporidians, and sporozoans, as well as their closest free-living relatives, we reveal the evolutionary trajectories and adaptations that enabled the transition to intracellular parasitism. Intracellular parasites have evolved various efficient mechanisms for host acquisition and exploitation, allowing them to thrive in a variety of hosts. Each group has developed unique features related to the parasitic lifestyle, involving dedicated protein families associated with host cell invasion, survival, and exit. Indeed, parallel evolution has led to distinct lineages of intracellular parasites employing diverse traits and approaches to achieve similar outcomes.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Annual Review of Microbiology

ISSN

0066-4227

e-ISSN

1545-3251

Svazek periodika

78

Číslo periodika v rámci svazku

APR

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

21

Strana od-do

39-59

Kód UT WoS článku

001362413800004

EID výsledku v databázi Scopus

2-s2.0-85210453611