Advancements in compound-specific hydrogen stable-isotope analysis of fatty and amino acids

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F25%3A00635686" target="_blank" >RIV/60077344:_____/25:00635686 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0165993625000627?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0165993625000627?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.trac.2025.118194" target="_blank" >10.1016/j.trac.2025.118194</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Advancements in compound-specific hydrogen stable-isotope analysis of fatty and amino acids

Popis výsledku v původním jazyce

This review explores advancements in compound-specific hydrogen stable isotope (δ2H) analysis (CSIA) of amino and fatty acids from biological samples, highlighting their increased applicability in ecological, environmental, and physiological research. We discuss the current analytical capabilities and limitations of δ2H-CSIA, emphasizing important technical challenges associated with hydrogen isotope exchange of samples with ambient moisture and detection limitations posed by the low natural abundance of deuterium. Key developments in gas chromatography-isotope ratio mass spectrometry (GC-IRMS) are detailed, illustrating their role in improving our ability to trace metabolic, ecological and environmental processes. Topics include strategies for addressing the challenges of exchangeable hydrogen for amino acids, recent technological improvements to improve IRMS precision for δ2H-CSIA, and the potential for new applications in ecological research, food authenticity, and palaeoecological studies. This review underscores that ongoing progress and improvements in CSIA technology are required for future research to further our understanding of ecological and nutritional dynamics.

Název v anglickém jazyce

Advancements in compound-specific hydrogen stable-isotope analysis of fatty and amino acids

Popis výsledku anglicky

This review explores advancements in compound-specific hydrogen stable isotope (δ2H) analysis (CSIA) of amino and fatty acids from biological samples, highlighting their increased applicability in ecological, environmental, and physiological research. We discuss the current analytical capabilities and limitations of δ2H-CSIA, emphasizing important technical challenges associated with hydrogen isotope exchange of samples with ambient moisture and detection limitations posed by the low natural abundance of deuterium. Key developments in gas chromatography-isotope ratio mass spectrometry (GC-IRMS) are detailed, illustrating their role in improving our ability to trace metabolic, ecological and environmental processes. Topics include strategies for addressing the challenges of exchangeable hydrogen for amino acids, recent technological improvements to improve IRMS precision for δ2H-CSIA, and the potential for new applications in ecological research, food authenticity, and palaeoecological studies. This review underscores that ongoing progress and improvements in CSIA technology are required for future research to further our understanding of ecological and nutritional dynamics.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

TrAC-Trends in Analytical Chemistry

ISSN

0165-9936

e-ISSN

1879-3142

Svazek periodika

186

Číslo periodika v rámci svazku

May

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

118194

Kód UT WoS článku

001440072500001

EID výsledku v databázi Scopus

2-s2.0-85217753905