Physiology of the tick midgut

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F25%3A00644907" target="_blank" >RIV/60077344:_____/25:00644907 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/bs.aiip.2025.04.002" target="_blank" >https://doi.org/10.1016/bs.aiip.2025.04.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/bs.aiip.2025.04.002" target="_blank" >10.1016/bs.aiip.2025.04.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Physiology of the tick midgut

Popis výsledku v původním jazyce

Ticks are obligate hematophagous ectoparasites that have evolved a highly specialized feeding strategy, enabling them to ingest exceptionally large volumes of host blood, often containing pathogenic microbes. As vectors of numerous infectious agents, ticks have a significant impact on human and animal health worldwide. Central to their success as blood feeders and disease vectors is the midgut—a multifunctional organ that mediates nutrient uptake, immune responses, and interactions with invading pathogens. This chapter reviews the current state of knowledge on the physiology of the tick midgut from both structural (morphological) and functional perspectives, focusing on blood meal processing, heme homeostasis, and innate immunity. In addition, recent advances in omics technologies are presented, which have provided valuable insights into the molecular and microbiological underpinnings of tick midgut function, as well as the role of the midgut microbiota in tick physiology and vector competence. A detailed understanding of these physiological processes is essential for identifying new targets to disrupt tick feeding and pathogen transmission, thereby contributing to the development of effective tick control strategies.

Název v anglickém jazyce

Physiology of the tick midgut

Popis výsledku anglicky

Ticks are obligate hematophagous ectoparasites that have evolved a highly specialized feeding strategy, enabling them to ingest exceptionally large volumes of host blood, often containing pathogenic microbes. As vectors of numerous infectious agents, ticks have a significant impact on human and animal health worldwide. Central to their success as blood feeders and disease vectors is the midgut—a multifunctional organ that mediates nutrient uptake, immune responses, and interactions with invading pathogens. This chapter reviews the current state of knowledge on the physiology of the tick midgut from both structural (morphological) and functional perspectives, focusing on blood meal processing, heme homeostasis, and innate immunity. In addition, recent advances in omics technologies are presented, which have provided valuable insights into the molecular and microbiological underpinnings of tick midgut function, as well as the role of the midgut microbiota in tick physiology and vector competence. A detailed understanding of these physiological processes is essential for identifying new targets to disrupt tick feeding and pathogen transmission, thereby contributing to the development of effective tick control strategies.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

10601 - Cell biology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Advances in Insect Physiology

ISBN

9780443314186

Počet stran výsledku

64

Strana od-do

89-152

Počet stran knihy

184

Název nakladatele

Elsevier

Místo vydání

Londýn

Kód UT WoS kapitoly

—