Projekty helmintích genomů: vše nebo nic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077409%3A_____%2F05%3A00025505" target="_blank" >RIV/60077409:_____/05:00025505 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12310/05:00008717

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Helminth genome projects: all or nothing

Popis výsledku v původním jazyce

Genomes of parasites that infect humans are being sequenced at a growing pace. The whole genomes of a number of protozoans have been sequenced, with Plasmodium spp., trypanosomes and Leishmania major leading the field. In fact, all the most serious protozoan parasites of humans will have their genome sequence completed soon. Because of their geographical distribution, filariae such as Loa loa and Dracunculus medinensis are hard to obtain, non-fixed, in sufficient quantity, thus hampering their suitability for molecular studies. However, this problem certainly does not apply to the pinworm and other globally present and frequent helminth parasites, which remain under-represented or even absent in the databases. Is it the lack of a model host, legal aspects, ethical problems, technical difficulties, the large size of some helminth genomes, or simply a matter of prioritisation of limited funding that deters molecular biologists from touching these important organisms?

Název v anglickém jazyce

Helminth genome projects: all or nothing

Popis výsledku anglicky

Genomes of parasites that infect humans are being sequenced at a growing pace. The whole genomes of a number of protozoans have been sequenced, with Plasmodium spp., trypanosomes and Leishmania major leading the field. In fact, all the most serious protozoan parasites of humans will have their genome sequence completed soon. Because of their geographical distribution, filariae such as Loa loa and Dracunculus medinensis are hard to obtain, non-fixed, in sufficient quantity, thus hampering their suitability for molecular studies. However, this problem certainly does not apply to the pinworm and other globally present and frequent helminth parasites, which remain under-represented or even absent in the databases. Is it the lack of a model host, legal aspects, ethical problems, technical difficulties, the large size of some helminth genomes, or simply a matter of prioritisation of limited funding that deters molecular biologists from touching these important organisms?

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EG - Zoologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Trends in Parasitology

ISSN

1471-4922

e-ISSN

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Svazek periodika

21

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

2

Strana od-do

265-266

Kód UT WoS článku

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EID výsledku v databázi Scopus

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