A comparison of the neuroprotective efficacy of newly developed oximes (K203, K206) and commonly used oximes (obidoxime, HI-6) in tabun-poisoned rats

Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F09%3A00002101" target="_blank" >RIV/60162694:G44__/09:00002101 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Jazyk výsledku
angličtina
Název v původním jazyce
A comparison of the neuroprotective efficacy of newly developed oximes (K203, K206) and commonly used oximes (obidoxime, HI-6) in tabun-poisoned rats
Popis výsledku v původním jazyce
The neuroprotective efficacy of commonly used oximes (obidoxime and HI-6) as well as one of newly synthesized oxime (K206) is significantly lower in comparison with K203 according to the number of eliminated tabun-induced neurotoxic signs at 24 hours after tabun challenge. Due to its neuroprotective effects, K203 appears to be suitable oxime for the antidotal treatment of acute tabun poisonings.
Název v anglickém jazyce
A comparison of the neuroprotective efficacy of newly developed oximes (K203, K206) and commonly used oximes (obidoxime, HI-6) in tabun-poisoned rats
Popis výsledku anglicky
The neuroprotective efficacy of commonly used oximes (obidoxime and HI-6) as well as one of newly synthesized oxime (K206) is significantly lower in comparison with K203 according to the number of eliminated tabun-induced neurotoxic signs at 24 hours after tabun challenge. Due to its neuroprotective effects, K203 appears to be suitable oxime for the antidotal treatment of acute tabun poisonings.

Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FP - Ostatní lékařské obory
OECD FORD obor
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Rok uplatnění
2009
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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