A comparison of reactivating and therapeutic efficacy of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice

Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F09%3A00002102" target="_blank" >RIV/60162694:G44__/09:00002102 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Jazyk výsledku
angličtina
Název v původním jazyce
A comparison of reactivating and therapeutic efficacy of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice
Popis výsledku v původním jazyce
Although the reactivating and therapeutic efficacy of the oxime K203 is higher compared to another newly developed oxime K156, the reactivating and therapeutic potency of both newly developed oximes is significantly lower in comparison with the oxime HI-6 and therefore, none of them is suitable for replacement of HI-6 by them in the case of the treatment of cyclosarin poisoning.
Název v anglickém jazyce
A comparison of reactivating and therapeutic efficacy of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice
Popis výsledku anglicky
Although the reactivating and therapeutic efficacy of the oxime K203 is higher compared to another newly developed oxime K156, the reactivating and therapeutic potency of both newly developed oximes is significantly lower in comparison with the oxime HI-6 and therefore, none of them is suitable for replacement of HI-6 by them in the case of the treatment of cyclosarin poisoning.

Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FP - Ostatní lékařské obory
OECD FORD obor
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Rok uplatnění
2009
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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