Effect of some pyridinium based compounds on the hydrolysis of carboxylate ester
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F12%3A43874658" target="_blank" >RIV/60162694:G44__/12:43874658 - isvavai.cz</a>
Výsledek na webu
<a href="http://nopr.niscair.res.in/bitstream/123456789/13828/1/IJCB%2051B%284%29%20611-616.pdf" target="_blank" >http://nopr.niscair.res.in/bitstream/123456789/13828/1/IJCB%2051B%284%29%20611-616.pdf</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Effect of some pyridinium based compounds on the hydrolysis of carboxylate ester
Popis výsledku v původním jazyce
Nucleophilic reactivity of some pyridinium based compounds towards hydrolysis of p-nitrophenyl acetate (PNPA) has been studied at pH 9.0 and temperature 27? C. The nucleophilic reactivity of newly synthesized pyridinium compounds has been compared with commercially available pyridinium based compounds such as pralidoxime and dodecylpyridinium bromide. It has been observed that with an increase in the concentration of these compounds there is an increase in the first order rate constant of the reaction.The apparent acid dissociation constant (pKa) of some compounds have also been determined spectrophotometrically. Oximate ions released from 3-hydroxyiminomethyl-1-dodecylpyridinium bromide (3-HIDDPB) and pralidoxime have proved to be better nucleophilicagents for cleavage of carboxylate ester. Present investigation explores the structure-activity relationship of some pyridinium based compounds with same alkyl tail length.
Název v anglickém jazyce
Effect of some pyridinium based compounds on the hydrolysis of carboxylate ester
Popis výsledku anglicky
Nucleophilic reactivity of some pyridinium based compounds towards hydrolysis of p-nitrophenyl acetate (PNPA) has been studied at pH 9.0 and temperature 27? C. The nucleophilic reactivity of newly synthesized pyridinium compounds has been compared with commercially available pyridinium based compounds such as pralidoxime and dodecylpyridinium bromide. It has been observed that with an increase in the concentration of these compounds there is an increase in the first order rate constant of the reaction.The apparent acid dissociation constant (pKa) of some compounds have also been determined spectrophotometrically. Oximate ions released from 3-hydroxyiminomethyl-1-dodecylpyridinium bromide (3-HIDDPB) and pralidoxime have proved to be better nucleophilicagents for cleavage of carboxylate ester. Present investigation explores the structure-activity relationship of some pyridinium based compounds with same alkyl tail length.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CC - Organická chemie
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/OVUOFVZ200803" target="_blank" >OVUOFVZ200803: SUBSTANCE - Vývoj nového činidla pro dekontaminaci a dezinfekci kůže na bázi micelárních substancí</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Indian Journal of Chemistry Section B
ISSN
0376-4699
e-ISSN
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Svazek periodika
51
Číslo periodika v rámci svazku
4
Stát vydavatele periodika
IN - Indická republika
Počet stran výsledku
6
Strana od-do
611-616
Kód UT WoS článku
000303304700002
EID výsledku v databázi Scopus
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