Biosensors for the diagnosis of celiac disease: current status and future perspectives

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F16%3A43875595" target="_blank" >RIV/60162694:G44__/16:43875595 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16370/16:43874612

Výsledek na webu

<a href="http://link.springer.com/article/10.1007%2Fs12033-016-9940-3" target="_blank" >http://link.springer.com/article/10.1007%2Fs12033-016-9940-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s12033-016-9940-3" target="_blank" >10.1007/s12033-016-9940-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Biosensors for the diagnosis of celiac disease: current status and future perspectives

Popis výsledku v původním jazyce

Celiac disease (CD) is an autoimmune enteropathy initiated and sustained by the ingestion of gluten in genetically susceptible individuals. It is caused by a dysregulated immune response toward both dietary antigens, the gluten proteins of wheat, rye, and barley, and autoantigens, the enzyme tissue transglutaminase (TG2). The small intestine is the target organ. Although routine immunochemical protocols for a laboratory diagnosis of CD are available, faster, easier-to-use, and cheaper analytical devices for CD diagnosis are currently unavailable. This review focuses on biosensors, consisting of a physicochemical transducer and a bioreceptor, as promising analytical tools for diagnosis of CD and other diseases. Examples of recently developed biosensors as well as expectations for future lines of research and development in this field are presented.

Název v anglickém jazyce

Biosensors for the diagnosis of celiac disease: current status and future perspectives

Popis výsledku anglicky

Celiac disease (CD) is an autoimmune enteropathy initiated and sustained by the ingestion of gluten in genetically susceptible individuals. It is caused by a dysregulated immune response toward both dietary antigens, the gluten proteins of wheat, rye, and barley, and autoantigens, the enzyme tissue transglutaminase (TG2). The small intestine is the target organ. Although routine immunochemical protocols for a laboratory diagnosis of CD are available, faster, easier-to-use, and cheaper analytical devices for CD diagnosis are currently unavailable. This review focuses on biosensors, consisting of a physicochemical transducer and a bioreceptor, as promising analytical tools for diagnosis of CD and other diseases. Examples of recently developed biosensors as well as expectations for future lines of research and development in this field are presented.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EI - Biotechnologie a bionika

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Molecular Biotechnology

ISSN

1073-6085

e-ISSN

—

Svazek periodika

58

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

12

Strana od-do

381-392

Kód UT WoS článku

000376600900001

EID výsledku v databázi Scopus

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