Fate of tris(2-chloroethyl)amine in water and alkaline environment determined by thin-layer chromatography and gas chromatography–mass spectrometry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG45__%2F21%3A00556429" target="_blank" >RIV/60162694:G45__/21:00556429 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007%2Fs00764-020-00072-7" target="_blank" >https://link.springer.com/article/10.1007%2Fs00764-020-00072-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00764-020-00072-7" target="_blank" >10.1007/s00764-020-00072-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fate of tris(2-chloroethyl)amine in water and alkaline environment determined by thin-layer chromatography and gas chromatography–mass spectrometry

Popis výsledku v původním jazyce

Tris(2-chloroethyl)amine is a chemical warfare agent which is considered to be a persistent contaminant highly resistant to decontamination. The time dependence of tris(2-chloroethyl)amine degradation on the water pH value is observed to determine decontamination options using the decontamination of hydroxide-based mixtures which are used by a number of armed forces. The kinetics was observed using thin-layer chromatography and gas chromatography. The time development of tris(2-chloroethyl)amine concentration decrease in the environment with the pH ranging from 7.5 to 12.5 was recorded. The reaction rate constants were established at all observed pH values, half-lifes of reactions and the influence of temperature on the reaction rate at a slightly alkaline pH of 8.5. The equation to estimate the rate constant of the first step of tris(2-chloroethyl)amine hydrolysis at various temperatures was formed. The rate of triethanolamine formation in the samples of neutral to alkaline pH was recorded. The results indicate the substantial influence of pH on tris(2-chloroethyl)amine hydrolysis. The rate constant was significantly increased from neutral environment to the pH of 12.5 reaching 500% of the original value using alkalisation. The hydrolysis in neutral environment was also influenced by the analyte concentration. The concentrated solutions hydrolysed more slowly as a result of hydrochloric acid release as for the acid lowered the pH value of environment. The results demonstrate that there is an important kinetic difference between sulfur and nitrogen mustard hydrolysis in alkaline environment.

Název v anglickém jazyce

Fate of tris(2-chloroethyl)amine in water and alkaline environment determined by thin-layer chromatography and gas chromatography–mass spectrometry

Popis výsledku anglicky

Tris(2-chloroethyl)amine is a chemical warfare agent which is considered to be a persistent contaminant highly resistant to decontamination. The time dependence of tris(2-chloroethyl)amine degradation on the water pH value is observed to determine decontamination options using the decontamination of hydroxide-based mixtures which are used by a number of armed forces. The kinetics was observed using thin-layer chromatography and gas chromatography. The time development of tris(2-chloroethyl)amine concentration decrease in the environment with the pH ranging from 7.5 to 12.5 was recorded. The reaction rate constants were established at all observed pH values, half-lifes of reactions and the influence of temperature on the reaction rate at a slightly alkaline pH of 8.5. The equation to estimate the rate constant of the first step of tris(2-chloroethyl)amine hydrolysis at various temperatures was formed. The rate of triethanolamine formation in the samples of neutral to alkaline pH was recorded. The results indicate the substantial influence of pH on tris(2-chloroethyl)amine hydrolysis. The rate constant was significantly increased from neutral environment to the pH of 12.5 reaching 500% of the original value using alkalisation. The hydrolysis in neutral environment was also influenced by the analyte concentration. The concentrated solutions hydrolysed more slowly as a result of hydrochloric acid release as for the acid lowered the pH value of environment. The results demonstrate that there is an important kinetic difference between sulfur and nitrogen mustard hydrolysis in alkaline environment.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Planar Chromatography - Modern TLC

ISSN

0933-4173

e-ISSN

1789-0993

Svazek periodika

33

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

HU - Maďarsko

Počet stran výsledku

9

Strana od-do

669-677

Kód UT WoS článku

000604867300002

EID výsledku v databázi Scopus

2-s2.0-85098800234