Hodnocení stupně poškození DNA, toxicity a mutagenity vyvolané působením olova v rostlinách tabáku

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F08%3A24264" target="_blank" >RIV/60460709:41210/08:24264 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Evaluation of DNA damage, toxicity and mutagenicity induced by lead in tobacco plants

Popis výsledku v původním jazyce

Tobacco (Nicotiana tabacum L. var. xanthi) seedlings were treated with water solutions of lead nitrate (Pb2+) at concentrations ranging from 25 ?M to 2.4 mM for 24 h and 7 days. Pb content in the soil and in the plants was measured by inductively coupledplasma optical emission spectrometry. The DNA damage measured by the comet assay was high in the root nuclei, but in the leaf nuclei a slight but significant increase in DNA damage could be demonstrated only after day 7 with 200 ?M Pb2+ treatment. In tobacco plants growing for 6 weeks in soil polluted with Pb2+ severe toxic effects, expressed by the decrease in leaf area, and a slight but significant increase in DNA damage were observed. The tobacco plants with increased extent of DNA damage were severely injured exhibiting stunted growth, distorted leaves and brown root tips. This increase in DNA damage may be associated with necrotic or apoptotic DNA fragmentation. The frequency of somatic mutations in tobacco plants growing in the P

Název v anglickém jazyce

Evaluation of DNA damage, toxicity and mutagenicity induced by lead in tobacco plants

Popis výsledku anglicky

Tobacco (Nicotiana tabacum L. var. xanthi) seedlings were treated with water solutions of lead nitrate (Pb2+) at concentrations ranging from 25 ?M to 2.4 mM for 24 h and 7 days. Pb content in the soil and in the plants was measured by inductively coupledplasma optical emission spectrometry. The DNA damage measured by the comet assay was high in the root nuclei, but in the leaf nuclei a slight but significant increase in DNA damage could be demonstrated only after day 7 with 200 ?M Pb2+ treatment. In tobacco plants growing for 6 weeks in soil polluted with Pb2+ severe toxic effects, expressed by the decrease in leaf area, and a slight but significant increase in DNA damage were observed. The tobacco plants with increased extent of DNA damage were severely injured exhibiting stunted growth, distorted leaves and brown root tips. This increase in DNA damage may be associated with necrotic or apoptotic DNA fragmentation. The frequency of somatic mutations in tobacco plants growing in the P

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Mutation Research-Genetic Toxicology and Environmental Mutagenesis

ISSN

1383-5718

e-ISSN

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Svazek periodika

652

Číslo periodika v rámci svazku

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Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

5

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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