The effect of risk factors of sheep flock management practices on the development of anthelmintic resistance in the Czech Republic

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F14%3A65513" target="_blank" >RIV/60460709:41210/14:65513 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The effect of risk factors of sheep flock management practices on the development of anthelmintic resistance in the Czech Republic

Popis výsledku v původním jazyce

The in vivo faecal egg count reduction test was used for the evaluation of the benzimidazole and macrocylic lactone drug efficacies against gastrointestinal nematodes in 10 flocks of sheep. The same samples were tested concurrently in vitro for benzimidazole resistance using the egg hatch test, and for resistance to ivermectins using the microagar larval development test. The conformity of obtained results between in vivo and in vitro tests was recorded. When the selected methods were applied, anthelmintic resistance to benzimidazoles was detected at four (40%) farms while resistance to ivermectins was evident at one (10%) farm. At one farm (10%) ivermectin resistance was suspected. Moxidectin was effective at all surveyed farms. Teladorsagia was recognized as the only benzimidazole resistant genus in post-treatment coprocultures, whereas Haemonchus larvae were resistant to ivermectins. This represents the first recorded occurrence of ivermectin resistance in gastrointestinal nematodes

Název v anglickém jazyce

The effect of risk factors of sheep flock management practices on the development of anthelmintic resistance in the Czech Republic

Popis výsledku anglicky

The in vivo faecal egg count reduction test was used for the evaluation of the benzimidazole and macrocylic lactone drug efficacies against gastrointestinal nematodes in 10 flocks of sheep. The same samples were tested concurrently in vitro for benzimidazole resistance using the egg hatch test, and for resistance to ivermectins using the microagar larval development test. The conformity of obtained results between in vivo and in vitro tests was recorded. When the selected methods were applied, anthelmintic resistance to benzimidazoles was detected at four (40%) farms while resistance to ivermectins was evident at one (10%) farm. At one farm (10%) ivermectin resistance was suspected. Moxidectin was effective at all surveyed farms. Teladorsagia was recognized as the only benzimidazole resistant genus in post-treatment coprocultures, whereas Haemonchus larvae were resistant to ivermectins. This represents the first recorded occurrence of ivermectin resistance in gastrointestinal nematodes

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

<a href="/cs/project/QI111A199" target="_blank" >QI111A199: Efektivní systém prevence parazitóz v chovu ovcí</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Small Ruminant Research

ISSN

0921-4488

e-ISSN

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Svazek periodika

117

Číslo periodika v rámci svazku

2-3

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

183-190

Kód UT WoS článku

000332192800011

EID výsledku v databázi Scopus

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