In vitro growth-inhibitory activity of Calophyllum inophyllum ethanol leaf extract against diarrhoea-causing bacteria
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F17%3A74149" target="_blank" >RIV/60460709:41210/17:74149 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/60460709:41340/17:74149
Výsledek na webu
<a href="http://dx.doi.org/10.4314/tjpr.v16i9.23" target="_blank" >http://dx.doi.org/10.4314/tjpr.v16i9.23</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4314/tjpr.v16i9.23" target="_blank" >10.4314/tjpr.v16i9.23</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
In vitro growth-inhibitory activity of Calophyllum inophyllum ethanol leaf extract against diarrhoea-causing bacteria
Popis výsledku v původním jazyce
Purpose: To investigate the in vitro growth-inhibitory effect of Calophyllum inophyllum, a medicinal plant traditionally used to cure gastrointestinal disorders caused by diarrhoea-causing bacteria. Methods: The minimum inhibitory concentration (MIC) of C. inophyllum ethanol leaf extract was determined against six diarrhoea-causing bacteria, namely, Clostridium difficile infant, Clostridium perfringens, Enterococcus faecalis, Escherichia coli, Listeria monocytogenes, and Salmonella enterica. The effect of the plant extract on bacterial growth kinetics was further evaluated by slightly modified broth microdilution method. Results: The plant extract showed significant inhibitory activity against C. perfringens and L. monocytogenes (MIC = 128 microg/mL) followed by C. difficile (MIC = 512 micro/mL). Monitored growth curves also showed that the plant extract at 0,5 MIC inhibits bacterial growth by distinct extension of the lag phase or suppression of the whole growth rate in C. difficile and L. monocytog
Název v anglickém jazyce
In vitro growth-inhibitory activity of Calophyllum inophyllum ethanol leaf extract against diarrhoea-causing bacteria
Popis výsledku anglicky
Purpose: To investigate the in vitro growth-inhibitory effect of Calophyllum inophyllum, a medicinal plant traditionally used to cure gastrointestinal disorders caused by diarrhoea-causing bacteria. Methods: The minimum inhibitory concentration (MIC) of C. inophyllum ethanol leaf extract was determined against six diarrhoea-causing bacteria, namely, Clostridium difficile infant, Clostridium perfringens, Enterococcus faecalis, Escherichia coli, Listeria monocytogenes, and Salmonella enterica. The effect of the plant extract on bacterial growth kinetics was further evaluated by slightly modified broth microdilution method. Results: The plant extract showed significant inhibitory activity against C. perfringens and L. monocytogenes (MIC = 128 microg/mL) followed by C. difficile (MIC = 512 micro/mL). Monitored growth curves also showed that the plant extract at 0,5 MIC inhibits bacterial growth by distinct extension of the lag phase or suppression of the whole growth rate in C. difficile and L. monocytog
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
21101 - Food and beverages
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2017
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH
ISSN
1596-5996
e-ISSN
—
Svazek periodika
16
Číslo periodika v rámci svazku
9
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
7
Strana od-do
2207-2213
Kód UT WoS článku
000418444300022
EID výsledku v databázi Scopus
2-s2.0-85030546221