Influence of human milk oligosaccharides on adherence of bifidobacteria and clostridia to cell lines
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F17%3A75035" target="_blank" >RIV/60460709:41210/17:75035 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1556/030.64.2017.029" target="_blank" >http://dx.doi.org/10.1556/030.64.2017.029</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1556/030.64.2017.029" target="_blank" >10.1556/030.64.2017.029</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Influence of human milk oligosaccharides on adherence of bifidobacteria and clostridia to cell lines
Popis výsledku v původním jazyce
Adhesion of gut bacteria to the intestinal epithelium is the first step in their colonization of the neonatal immature gut. Bacterial colonization of the infant gut is influenced by several factors, of which the most important are the mode of delivery and breast-feeding. Breast-fed infants ingest several grams of human milk oligosaccharides (HMOs) per day, which can become receptor decoys for intestinal bacteria. The most abundant intestinal bacteria in vaginally delivered infants are bifidobacteria, whereas infants born by cesarean section are colonized by clostridia. The influence of HMOs on the adhesion of five strains of intestinal bacteria (three bifidobacterial strains and two clostridial strains) to mucus-secreting and non-mucus-secreting human epithelial cells was investigated. Bifidobacterium bifidum 1 and Bifidobacterium longum displayed almost the same level of adhesion in the presence and absence of HMOs. By contrast, adhesion of Clostridium butyricum 1 and 2 decreased from 14,41% to 6,7
Název v anglickém jazyce
Influence of human milk oligosaccharides on adherence of bifidobacteria and clostridia to cell lines
Popis výsledku anglicky
Adhesion of gut bacteria to the intestinal epithelium is the first step in their colonization of the neonatal immature gut. Bacterial colonization of the infant gut is influenced by several factors, of which the most important are the mode of delivery and breast-feeding. Breast-fed infants ingest several grams of human milk oligosaccharides (HMOs) per day, which can become receptor decoys for intestinal bacteria. The most abundant intestinal bacteria in vaginally delivered infants are bifidobacteria, whereas infants born by cesarean section are colonized by clostridia. The influence of HMOs on the adhesion of five strains of intestinal bacteria (three bifidobacterial strains and two clostridial strains) to mucus-secreting and non-mucus-secreting human epithelial cells was investigated. Bifidobacterium bifidum 1 and Bifidobacterium longum displayed almost the same level of adhesion in the presence and absence of HMOs. By contrast, adhesion of Clostridium butyricum 1 and 2 decreased from 14,41% to 6,7
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10606 - Microbiology
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2017
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA
ISSN
1217-8950
e-ISSN
—
Svazek periodika
64
Číslo periodika v rámci svazku
4
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
8
Strana od-do
415-422
Kód UT WoS článku
000418339500005
EID výsledku v databázi Scopus
2-s2.0-85038631483