The immunophilin repertoire of Plasmodiophora brassicae and functional analysis of PbCYP3 cyclophilin

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A74926" target="_blank" >RIV/60460709:41210/18:74926 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027006:_____/18:00004475

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00438-017-1395-0" target="_blank" >http://dx.doi.org/10.1007/s00438-017-1395-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00438-017-1395-0" target="_blank" >10.1007/s00438-017-1395-0</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The immunophilin repertoire of Plasmodiophora brassicae and functional analysis of PbCYP3 cyclophilin

Popis výsledku v původním jazyce

Plasmodiophora brassicae is a soil borne pathogen that belongs to Rhizaria, an almost unexplored eukaryotic organism group. This pathogen requires a living host for growth and multiplication, which makes molecular analysis further complicated. To broaden our understanding of a plasmodiophorid such as P. brassicae, we here chose to study immunophilins, a group of proteins known to have various cellular functions, including involvement in plant defense and pathogen virulence. Searches in the P. brassicae genome resulted in 20 putative immunophilins comprising of 11 cyclophilins (CYPs), 7 FK506 binding proteins (FKBPs) and 2 parvulin like proteins. RNAseq data showed that immunophilins were differentially regulated in enriched life stages such as germinating spores, maturing spores, and plasmodia, and infected Brassica hosts (B. rapa, B. napus and B. oleracea). PbCYP3 was highly induced in all studied life stages and during infection of all three Brassica hosts, and hence was selected for further analys

Název v anglickém jazyce

The immunophilin repertoire of Plasmodiophora brassicae and functional analysis of PbCYP3 cyclophilin

Popis výsledku anglicky

Plasmodiophora brassicae is a soil borne pathogen that belongs to Rhizaria, an almost unexplored eukaryotic organism group. This pathogen requires a living host for growth and multiplication, which makes molecular analysis further complicated. To broaden our understanding of a plasmodiophorid such as P. brassicae, we here chose to study immunophilins, a group of proteins known to have various cellular functions, including involvement in plant defense and pathogen virulence. Searches in the P. brassicae genome resulted in 20 putative immunophilins comprising of 11 cyclophilins (CYPs), 7 FK506 binding proteins (FKBPs) and 2 parvulin like proteins. RNAseq data showed that immunophilins were differentially regulated in enriched life stages such as germinating spores, maturing spores, and plasmodia, and infected Brassica hosts (B. rapa, B. napus and B. oleracea). PbCYP3 was highly induced in all studied life stages and during infection of all three Brassica hosts, and hence was selected for further analys

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

MOLECULAR GENETICS AND GENOMICS

ISSN

1617-4615

e-ISSN

1617-4615

Svazek periodika

293

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

10

Strana od-do

381-390

Kód UT WoS článku

000427630400007

EID výsledku v databázi Scopus

2-s2.0-85033503113