Initial butyrate producers during infant gut microbiota development are endospore formers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F20%3A83529" target="_blank" >RIV/60460709:41210/20:83529 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1111/1462-2920.15167" target="_blank" >https://doi.org/10.1111/1462-2920.15167</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/1462-2920.15167" target="_blank" >10.1111/1462-2920.15167</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Initial butyrate producers during infant gut microbiota development are endospore formers

Popis výsledku v původním jazyce

The acquisition of the infant gut microbiota is key to establishing a host-microbiota symbiosis. Microbially produced metabolites tightly interact with the immune system, and the fermentation-derived short-chain fatty acid butyrate is considered an important mediator linked to chronic diseases later in life. The intestinal butyrate-forming bacterial population is taxonomically and functionally diverse and includes endospore formers with high transmission potential. Succession, and contribution of butyrate-producing taxa during infant gut microbiota development have been little investigated. We determined the abundance of major butyrate-forming groups and fermentation metabolites in faeces, isolated, cultivated and characterized the heat-resistant cell population, which included endospores, and compared butyrate formation efficiency of representative taxa in batch cultures. The endospore community contributed about 0,001% to total cells, and was mainly composed of the pioneer butyrate-producingClostri

Název v anglickém jazyce

Initial butyrate producers during infant gut microbiota development are endospore formers

Popis výsledku anglicky

The acquisition of the infant gut microbiota is key to establishing a host-microbiota symbiosis. Microbially produced metabolites tightly interact with the immune system, and the fermentation-derived short-chain fatty acid butyrate is considered an important mediator linked to chronic diseases later in life. The intestinal butyrate-forming bacterial population is taxonomically and functionally diverse and includes endospore formers with high transmission potential. Succession, and contribution of butyrate-producing taxa during infant gut microbiota development have been little investigated. We determined the abundance of major butyrate-forming groups and fermentation metabolites in faeces, isolated, cultivated and characterized the heat-resistant cell population, which included endospores, and compared butyrate formation efficiency of representative taxa in batch cultures. The endospore community contributed about 0,001% to total cells, and was mainly composed of the pioneer butyrate-producingClostri

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10606 - Microbiology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Environmental Microbiology

ISSN

1462-2912

e-ISSN

—

Svazek periodika

22

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

13

Strana od-do

3909-3921

Kód UT WoS článku

000560944100001

EID výsledku v databázi Scopus

2-s2.0-85089585211