Effects of excessive dietary zinc or zinc/cadmium and tapeworm infection on the biochemical parameters in rats

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F21%3A85684" target="_blank" >RIV/60460709:41210/21:85684 - isvavai.cz</a>

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/abs/10.1111/jpn.13524" target="_blank" >https://onlinelibrary.wiley.com/doi/abs/10.1111/jpn.13524</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jpn.13524" target="_blank" >10.1111/jpn.13524</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effects of excessive dietary zinc or zinc/cadmium and tapeworm infection on the biochemical parameters in rats

Popis výsledku v původním jazyce

The main objective of this study was to determine which biochemical blood parameters can serve as indicators of Zn or Zn/Cd burden and tapeworm infection. This study was performed on 44 Wistar male rats during a 6week period, when rats were or were not fed a zinc/cadmium rich diet and were or were not infected with tapeworms (Hymenolepis diminuta). Total protein, albumin, urea, glucose, triacylglycerols, non esterified fatty acids, cholesterol, alkaline phosphatase, aspartate aminotransferase, uric acid, Mg, Ca, P and Zn levels were analysed. Control rats with tapeworm infection had significantly higher total protein, urea and phosphorus concentrations than did rats unaffected by any experimental factor. Rats given overdoses of zinc lactate exhibited significantly lower glucose levels than did the other rats, especially those infected with tapeworms. Low glucose level in uninfected rats indicate a Zn overdose, high doses of zinc lactate likely decrease levels of glucose via cortisol, which is release

Název v anglickém jazyce

Effects of excessive dietary zinc or zinc/cadmium and tapeworm infection on the biochemical parameters in rats

Popis výsledku anglicky

The main objective of this study was to determine which biochemical blood parameters can serve as indicators of Zn or Zn/Cd burden and tapeworm infection. This study was performed on 44 Wistar male rats during a 6week period, when rats were or were not fed a zinc/cadmium rich diet and were or were not infected with tapeworms (Hymenolepis diminuta). Total protein, albumin, urea, glucose, triacylglycerols, non esterified fatty acids, cholesterol, alkaline phosphatase, aspartate aminotransferase, uric acid, Mg, Ca, P and Zn levels were analysed. Control rats with tapeworm infection had significantly higher total protein, urea and phosphorus concentrations than did rats unaffected by any experimental factor. Rats given overdoses of zinc lactate exhibited significantly lower glucose levels than did the other rats, especially those infected with tapeworms. Low glucose level in uninfected rats indicate a Zn overdose, high doses of zinc lactate likely decrease levels of glucose via cortisol, which is release

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30310 - Parasitology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Animal Physiology and Animal Nutrition

ISSN

1439-0396

e-ISSN

1439-0396

Svazek periodika

105

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

989-995

Kód UT WoS článku

000633515000001

EID výsledku v databázi Scopus

2-s2.0-85103224770