OpiumPlex is a novel microsatellite system for profiling opium poppy (Papaver somniferum L.)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F21%3A88272" target="_blank" >RIV/60460709:41210/21:88272 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027006:_____/21:10150318 RIV/60461373:22330/21:43923676

Výsledek na webu

<a href="https://www.nature.com/articles/s41598-021-91962-1#citeas" target="_blank" >https://www.nature.com/articles/s41598-021-91962-1#citeas</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41598-021-91962-1" target="_blank" >10.1038/s41598-021-91962-1</a>

Jazyk výsledku

angličtina

Název v původním jazyce

OpiumPlex is a novel microsatellite system for profiling opium poppy (Papaver somniferum L.)

Popis výsledku v původním jazyce

Opium poppy (Papaver somniferum L.) is a versatile plant exploited by the pharmaceutical and food industries. Unfortunately, it is also infamously known as a source of highly addictive narcotics, primarily heroin. Drug abuse has devastating consequences for users and also has many direct or indirect negative impacts on human society as a whole. Therefore, developing a molecular genetic tool for the individualization of opium poppy, raw opium or heroin samples could help in the fight against the drug trade by retrieving more information about the source of narcotics and linking isolated criminal cases. Bioinformatic analysis provided insight into the distribution, density and other characteristics of roughly 150 thousand microsatellite loci within the poppy genome and indicated underrepresentation of microsatellites with the desired attributes. Despite this fact, 27 polymorphic STR markers, divided into three multiplexed assays, were developed in this work. Internal validation confirmed spec

Název v anglickém jazyce

OpiumPlex is a novel microsatellite system for profiling opium poppy (Papaver somniferum L.)

Popis výsledku anglicky

Opium poppy (Papaver somniferum L.) is a versatile plant exploited by the pharmaceutical and food industries. Unfortunately, it is also infamously known as a source of highly addictive narcotics, primarily heroin. Drug abuse has devastating consequences for users and also has many direct or indirect negative impacts on human society as a whole. Therefore, developing a molecular genetic tool for the individualization of opium poppy, raw opium or heroin samples could help in the fight against the drug trade by retrieving more information about the source of narcotics and linking isolated criminal cases. Bioinformatic analysis provided insight into the distribution, density and other characteristics of roughly 150 thousand microsatellite loci within the poppy genome and indicated underrepresentation of microsatellites with the desired attributes. Despite this fact, 27 polymorphic STR markers, divided into three multiplexed assays, were developed in this work. Internal validation confirmed spec

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10700 - Other natural sciences

Projekt

<a href="/cs/project/QK1720263" target="_blank" >QK1720263: Diagnostické metody pro laboratorní kontrolu pravosti máku setého</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Scientific Reports

ISSN

2045-2322

e-ISSN

2045-2322

Svazek periodika

11

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

15

Strana od-do

0-0

Kód UT WoS článku

000664915500025

EID výsledku v databázi Scopus

2-s2.0-85108067669