CRISPR-Based Genome Editing Tools: Insights into Technological Breakthroughs and Future Challenges

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F21%3A88659" target="_blank" >RIV/60460709:41210/21:88659 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.mdpi.com/2073-4425/12/6/797" target="_blank" >https://www.mdpi.com/2073-4425/12/6/797</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/genes12060797" target="_blank" >10.3390/genes12060797</a>

Jazyk výsledku

angličtina

Název v původním jazyce

CRISPR-Based Genome Editing Tools: Insights into Technological Breakthroughs and Future Challenges

Popis výsledku v původním jazyce

Genomeediting GE is having a tremendous influence around the globe in the life science community. Among its versatile uses, the desired modifications of genes, and more importantly the transgene DNAfree approach to develop genetically modified organism GMO, are of special interest. The recent and rapid developments in genomeediting technology have given rise to hopes to achieve global food security in a sustainable manner. We here discuss recent developments in CRISPRbased genomeediting tools for crop improvement concerning adaptation, opportunities, and challenges. Some of the notable advances highlighted here include the development of transgene DNAfree genome plants, the availability of compatible nucleases, and the development of safe and effective CRISPR delivery vehicles for plant genome editing, multigene targeting and complex genome editing, base editing and prime editing to achieve more complex genetic engineering. Additionally, new avenues that facilitate finetuning plant gene regulation ha

Název v anglickém jazyce

CRISPR-Based Genome Editing Tools: Insights into Technological Breakthroughs and Future Challenges

Popis výsledku anglicky

Genomeediting GE is having a tremendous influence around the globe in the life science community. Among its versatile uses, the desired modifications of genes, and more importantly the transgene DNAfree approach to develop genetically modified organism GMO, are of special interest. The recent and rapid developments in genomeediting technology have given rise to hopes to achieve global food security in a sustainable manner. We here discuss recent developments in CRISPRbased genomeediting tools for crop improvement concerning adaptation, opportunities, and challenges. Some of the notable advances highlighted here include the development of transgene DNAfree genome plants, the availability of compatible nucleases, and the development of safe and effective CRISPR delivery vehicles for plant genome editing, multigene targeting and complex genome editing, base editing and prime editing to achieve more complex genetic engineering. Additionally, new avenues that facilitate finetuning plant gene regulation ha

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10603 - Genetics and heredity (medical genetics to be 3)

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Genes

ISSN

2073-4425

e-ISSN

2073-4425

Svazek periodika

12

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

31

Strana od-do

1-31

Kód UT WoS článku

000667498800001

EID výsledku v databázi Scopus

2-s2.0-85107429839