Dirty-Hold Time Effect on the Cleaning Process Efficiency

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F12%3A43894830" target="_blank" >RIV/60461373:22310/12:43894830 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S1877705812028342" target="_blank" >http://www.sciencedirect.com/science/article/pii/S1877705812028342</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.proeng.2012.07.434" target="_blank" >10.1016/j.proeng.2012.07.434</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Dirty-Hold Time Effect on the Cleaning Process Efficiency

Popis výsledku v původním jazyce

The paper evaluated the efficiency of a standard cleaning procedure of the process equipment after production of anti hypertensive with the active component Losartan Potassium for different lengths of time between completion of production and the start of the treatment process - so called dirty-hold time. It has been found that the cleaning process is appropriately designed and efficient. The concentration of losartan in swabs from the equipments was in all cases within the limits of acceptance criteria. However, the washing process was in all cases sufficiently effective to meet the eligibility criteria, significant effect of the time of weaning of the contaminated equipment on the efficiency of the washing process was found. At studied dirty hold time horizon (0-4 days) there was a progressive deterioration of the efficiency of the cleaning process. It was found that the influence of the nature of the residual material on the cleaning process has minor effect then the length of the d

Název v anglickém jazyce

Dirty-Hold Time Effect on the Cleaning Process Efficiency

Popis výsledku anglicky

The paper evaluated the efficiency of a standard cleaning procedure of the process equipment after production of anti hypertensive with the active component Losartan Potassium for different lengths of time between completion of production and the start of the treatment process - so called dirty-hold time. It has been found that the cleaning process is appropriately designed and efficient. The concentration of losartan in swabs from the equipments was in all cases within the limits of acceptance criteria. However, the washing process was in all cases sufficiently effective to meet the eligibility criteria, significant effect of the time of weaning of the contaminated equipment on the efficiency of the washing process was found. At studied dirty hold time horizon (0-4 days) there was a progressive deterioration of the efficiency of the cleaning process. It was found that the influence of the nature of the residual material on the cleaning process has minor effect then the length of the d

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CI - Průmyslová chemie a chemické inženýrství

OECD FORD obor

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Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Procedia Engineering

ISSN

1877-7058

e-ISSN

—

Svazek periodika

42

Číslo periodika v rámci svazku

September

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

431-436

Kód UT WoS článku

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EID výsledku v databázi Scopus

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