Testování nanostrukturovaných povrchů

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F16%3A43903567" target="_blank" >RIV/60461373:22310/16:43903567 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

čeština

Název v původním jazyce

Testování nanostrukturovaných povrchů

Popis výsledku v původním jazyce

Direct connection of the implant with bone could be long term and difficult process. Surface of the titanium and its alloys can be bioactivated by nanostructuring. The growth of nanotubes is result of two simultaneous processes. First of them is anodic oxidation of the surface and the second one is the local dissolution of the growing titanium dioxide by fluoride ions. Morphology of tubes can be influenced by appropriate electrolyte and anodic polarization parameters. Nanostructured surfaces stimulate the deposition of osteoblast cells, which leads to easier integration of the implant into the bone. This work was focused on the nanostructuing of the Ti-6Al-4V alloy and on the studying of the nanostructures properties. For morphological characterization of samples, scanning electron microscope was used. X-ray photoelectron spectroscopy (XPS) was used for the surface analysis. The adhesion of the nanotubes was tested by a pull-off method and by scratch test. The biological properties of the nanostructures were studied with osteoblast like cells. Finally, in vivo tests with pigs were done. Based on the tests results, the nanostructuring seems to be a very promising surface treatment for medical implants made from titanium alloys. This surface treatment was successfully realized on real implants.

Název v anglickém jazyce

TITANIA NANOTUBULAR SURFACE TESTING

Popis výsledku anglicky

Direct connection of the implant with bone could be long term and difficult process. Surface of the titanium and its alloys can be bioactivated by nanostructuring. The growth of nanotubes is result of two simultaneous processes. First of them is anodic oxidation of the surface and the second one is the local dissolution of the growing titanium dioxide by fluoride ions. Morphology of tubes can be influenced by appropriate electrolyte and anodic polarization parameters. Nanostructured surfaces stimulate the deposition of osteoblast cells, which leads to easier integration of the implant into the bone. This work was focused on the nanostructuing of the Ti-6Al-4V alloy and on the studying of the nanostructures properties. For morphological characterization of samples, scanning electron microscope was used. X-ray photoelectron spectroscopy (XPS) was used for the surface analysis. The adhesion of the nanotubes was tested by a pull-off method and by scratch test. The biological properties of the nanostructures were studied with osteoblast like cells. Finally, in vivo tests with pigs were done. Based on the tests results, the nanostructuring seems to be a very promising surface treatment for medical implants made from titanium alloys. This surface treatment was successfully realized on real implants.

Druh

O - Ostatní výsledky

CEP obor

JK - Koroze a povrchové úpravy materiálu

OECD FORD obor

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Projekt

<a href="/cs/project/TE01020390" target="_blank" >TE01020390: Centrum vývoje moderních kovových biomateriálů pro lékařské implantáty</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů