A novel high-strength and highly corrosive biodegradable Fe-Pd alloy: Structural, mechanical and in vitro corrosion and cytotoxicity study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F17%3A43914209" target="_blank" >RIV/60461373:22310/17:43914209 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22330/17:43914209

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.msec.2017.05.100" target="_blank" >http://dx.doi.org/10.1016/j.msec.2017.05.100</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.msec.2017.05.100" target="_blank" >10.1016/j.msec.2017.05.100</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A novel high-strength and highly corrosive biodegradable Fe-Pd alloy: Structural, mechanical and in vitro corrosion and cytotoxicity study

Popis výsledku v původním jazyce

Recently, iron-based materials have been considered as candidates for the fabrication of biodegradable load bearing implants. Alloying with palladium has been found to be a suitable approach to enhance the insufficient corrosion rate of iron-based alloys. In this work, we have extensively compared the microstructure, the mechanical and corrosion properties, and the cytotoxicity of an FePd2 (wt%) alloy prepared by three different routes casting, mechanical alloying and spark plasma sintering (SPS), and mechanical alloying and the space holder technique (SHT). The properties of the FePd2 (wt%) were compared with pure Fe prepared in the same processes. The preparation route significantly influenced the material properties. Materials prepared by SPS-possessed the highest values of mechanical properties (CYS similar to 750-850 MPa) and higher corrosion rates than the casted materials. Materials prepared by SHT contained approximately 60% porosity; therefore, their mechanical properties reached the lowest values, and they had the highest corrosion rates, approximately 0.7-1.2 mm/a. Highly porous FePd2 was tested in vitro according to the ISO 10993-5 standard using L929 cells, and two-fold diluted extracts showed acceptable cytocompatibility. In general, alloying with Pd enhanced both mechanical properties and corrosion rates and did not decrease the cytocompatibility of the studied materials.

Název v anglickém jazyce

A novel high-strength and highly corrosive biodegradable Fe-Pd alloy: Structural, mechanical and in vitro corrosion and cytotoxicity study

Popis výsledku anglicky

Recently, iron-based materials have been considered as candidates for the fabrication of biodegradable load bearing implants. Alloying with palladium has been found to be a suitable approach to enhance the insufficient corrosion rate of iron-based alloys. In this work, we have extensively compared the microstructure, the mechanical and corrosion properties, and the cytotoxicity of an FePd2 (wt%) alloy prepared by three different routes casting, mechanical alloying and spark plasma sintering (SPS), and mechanical alloying and the space holder technique (SHT). The properties of the FePd2 (wt%) were compared with pure Fe prepared in the same processes. The preparation route significantly influenced the material properties. Materials prepared by SPS-possessed the highest values of mechanical properties (CYS similar to 750-850 MPa) and higher corrosion rates than the casted materials. Materials prepared by SHT contained approximately 60% porosity; therefore, their mechanical properties reached the lowest values, and they had the highest corrosion rates, approximately 0.7-1.2 mm/a. Highly porous FePd2 was tested in vitro according to the ISO 10993-5 standard using L929 cells, and two-fold diluted extracts showed acceptable cytocompatibility. In general, alloying with Pd enhanced both mechanical properties and corrosion rates and did not decrease the cytocompatibility of the studied materials.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20501 - Materials engineering

Projekt

<a href="/cs/project/GBP108%2F12%2FG043" target="_blank" >GBP108/12/G043: Mikro- a nanokrystalické materiály s vysokým podílem rozhraní pro moderní strukturní aplikace, biodegradabilní implantáty a uchovávání vodíku</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials science and engineering C

ISSN

0928-4931

e-ISSN

—

Svazek periodika

79

Číslo periodika v rámci svazku

october

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

13

Strana od-do

550-562

Kód UT WoS článku

000404704300065

EID výsledku v databázi Scopus

2-s2.0-85019421693